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OpenTrials
Completed

NCT Number: NCT02677363

Functional Outcomes of Stay Strong Stay Healthy Program

Strength training can increase muscle mass and strength while improving bone density and reducing risk for osteoporosis and related fractures. Strength training can also lead to reduced risk for diabetes, heart disease, arthritis, depression, and obesity; and improves self-confidence, sleep and vitality. Research demonstrates that strength training is extremely effective in helping aging adults with chronic conditions prevent further onset of disease and, in many instances, actually reverse the disease process. In Stay Strong, Stay Healthy Program elderly subjects perform resistance exercise training (RET) twice every week. Past literature suggests that resistance training improved muscle activity, muscle strength, muscle mass, and bone mineral density and total body composition, and adiponectin, insulin sensitivity, fasting blood-glucose (BG), HbA1c1 (long-term marker of BG), blood pressure (BP), blood triglycerides (TGs) and low density lipoproteins (LDL) in healthy and diabetic subjects. The purpose of this study is to measure the changes in the above discussed variables after 8-weeks of resistance exercises.

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Key information

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Missouri-Columbia

Columbia, Missouri, 65211, United States

About this study

Participants will perform resistance exercise for 8 weeks and measurements (anthropometric, electromyography, pulse wave velocity, strength test, dual x-ray absorptiometry, blood enzymes/hormones, and sleep, diet, memory surveys) will be performed pre- and post-exercise program.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 60 or above
  • Enrollment in Stay Strong Stay Healthy Program
  • Strength training < 2 hours/week for past 3 months

Exclusion criteria

  • Not enrolled in Stay Strong Stay Healthy Program
  • Strength training > 2 hours/week for past 3 months
  • Donated more than 463 ml of blood in past 8 weeks
  • Physician discouraged to participate

Treatment and study plan

Resistance Exercise

Other

Participants 60 and above aged (both females and males) will perform one hour of resistance exercise twice weekly for 8 weeks.

Other names: Strength training

Primary outcomes

  1. Muscle electrical activity

    Time frame: Change in muscle electrical activity in 8 weeks in response to resistance exercise program

    Measurement of muscle electrical activity is made using electromyography technique at baseline and after 8 weeks of resistance exercise.

Secondary outcomes

  1. Exert muscle power/strength

    Time frame: Change in muscle power/strength in 8 weeks in response to resistance exercise program

    Measurement of muscle power/strength is made using hand dynamometer at baseline and after 8 weeks of resistance exercise.

  2. Muscle mass loss

    Time frame: Change in muscle mass in 8 weeks in response to resistance exercise program

    Changes in the muscle mass is made using dual x-ray absorptiometry technique at baseline and after 8 weeks of resistance exercise.

  3. Ability to think or remember

    Time frame: Changes in thinking and cognitive abilities in 8 weeks in response to resistance exercise program

    Changes in ability to think or remember is measured by using standard survey (Self Administered Gerocognitive Exam Form -1) at baseline and after 8 weeks of resistance exercise.

Sponsors and collaborators

Lead sponsor

University of Missouri-Columbia

Other

Registry information

Official study title

Functional Outcomes of Stay Strong, Stay Healthy Program

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Feb 9, 2016
Registry last updated
Apr 3, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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