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Completed

NCT Number: NCT00542906

Functional Organization of Somatosensory Responses in the Secondary Somatosensitive Area and Insula

The implication of the second somatosensory area (SII) and the insular cortex in the processing of somatosensory inputs is now well established. However the functional anatomy of these areas hidden in the depth of the sylvian scissure remain mostly unknown.

The aim of this fMRI study is to determine the functional cartography of SII and insula. The localization of responses to different somatosensory stimuli (slight touch, warm, cold, heat pain and arthrokinesia) applied on the left hand of 25 healthy volunteers, will be compared.

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Key information

Conditions

Healthy

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Service de Neurologie - CHU de Saint-Etienne

Saint-Etienne, 42055, France

About this study

Aims : Demonstrate that localization of the several types of somatosensory stimuli is different into SII and into insula. If possible, we'll determine a functional cartography of these areas.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 25 healthy volunteers will be included ranging in age from 18 to 50 years
  • contraception needed for women
  • right handed
  • All the subjects have to give their written informed consent.

Exclusion criteria

  • pregnancy
  • neurological or psychiatric disease
  • drugs taken <12h before fMRI
  • contra-indications to fMRI : pacemaker, clip, metallic device
  • Refusing to be informed of the presence of a cerebral abnormality, detected during MRI.

Treatment and study plan

localization

Other

localization of the several types of somatosensory stimuli

Primary outcomes

  1. Comparison of euclidian distances between the centroids of clusters activations for the different types of stimulations into SII and insula.

    Time frame: one day

Secondary outcomes

  1. Determine the Talairach coordinates of the centroids of clusters of activations for the different types of somatosensory stimuli into SII and insula

    Time frame: one day

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Saint Etienne

Other

Registry information

Official study title

Functional Organization of Somatosensory Responses in the Secondary Somatosensitive Area (SII) and Insula : an fMRI Study

Important dates

Study start
2007
Primary completion
2008
Study completion
2008
First posted
Oct 12, 2007
Registry last updated
Jun 17, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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