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OpenTrials
Completed

NCT Number: NCT00481156

Functional Neuroimaging Effects of Cognitive Remediation Training

The purpose of this study is to examine behavioral and functional brain changes occuring as a result of cognitive remediation training in patients with schizophrenia. Extension and specificity of related changes will also be examined.

Completed

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Key information

Conditions

Schizophrenia Mental Disorders Schizophrenia Spectrum and Other Psychotic Disorders

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

University of Minnesota

Minneapolis, Minnesota, 55455, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of schizophrenia or schizoaffective disorder
  • Stable outpatient

Exclusion criteria

  • Current drug abuse or dependence
  • History of neurological damage, disorder, or disease

Treatment and study plan

Cognitive Remediation

Behavioral

Cognitive Behavioral Social Skills Training

Behavioral

Retest in Health Controls

Other

Pre/Post test performance and neuroimaging only

Primary outcomes

  1. Working Memory performance

    Time frame: Post-test

    N-Back Performance

  2. Brain activation

    Time frame: Post-test

    Changes in prefrontal cortical functioning

Sponsors and collaborators

Lead sponsor

University of Minnesota

Other

Collaborators

  • Minnesota Medical Foundation

Registry information

Important dates

Study start
2005
Primary completion
2007
Study completion
2007
First posted
Jun 1, 2007
Registry last updated
May 4, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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