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OpenTrials
Completed

NCT Number: NCT04958759

Functional Inspiratory Muscle Training in Chronic Kidney Disease

Effects of functional inspiratory muscle training by telerehabilitation on respiratory and peripheral functions, functional capacity, diaphragm thickness and mobility, posture, quality of life, cognitive function, fatigue, physical activity, endothelial function and aortic stiffness in patients with chronic kidney disease will be investigated.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hacettepe University, Faculty of Physical Therapy and Rehabilitation

Ankara, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with chronic kidney disease not receiving dialysis
  • Access to the online program
  • Volunteering to participate in the research

Exclusion criteria

  • Having a musculoskeletal problem
  • Having decompensated diabetes
  • Having uncontrolled hypertension

Treatment and study plan

Functional Inspiratory Muscle Training

Other

The inspiratory muscle training program will be consist of 4 weeks of foundation inspiratory muscle training and 6 weeks of functional inspiratory muscle training

Inspiratory Muscle Training

Other

The inspiratory muscle training program will be consist of 10 weeks of foundation inspiratory muscle training

Breathing exercises

Other

The program will be consist of 10 weeks of breathing exercises

Primary outcomes

  1. Respiratory muscle strength

    Time frame: 10 minutes

    Respiratory muscle strength will be evaluated using mouth pressure device

  2. Respiratory muscle endurance

    Time frame: 10 minutes

    Respiratory muscle endurance will be evaluated using incremental load test

  3. Pulmonary function

    Time frame: 5 minutes

    Pulmonary functions will be evaluated using spirometry

  4. Peripheral muscle strength

    Time frame: 5 minutes

    Peripheral muscle strength will be evaluated using dynamometer

  5. Endurance of trunk muscles

    Time frame: 10 minutes

    Endurance of trunk muscles will be evaluated using plank, side plank, flexor endurance and pelvic bridge test

  6. Lower extremity muscle endurance

    Time frame: 1 minutes

    Lower extremity muscle endurance will be evaluated using sit-to-stand test

  7. Functional capacity

    Time frame: 10 minutes

    Functional capacity will be evaluated using six-minute walk test

  8. Diaphragm thickness and mobility

    Time frame: 20 minutes

    Diaphragm thickness and mobility will be evaluated using ultrasonography

Secondary outcomes

  1. Balance

    Time frame: 5 minutes

    Balance will be evaluated using timed up and go test

  2. Static balance

    Time frame: 5 minutes

    Balance will be evaluated using one-legged standing test

  3. Posture

    Time frame: 5 minutes

    Posture will be evaluated using Corbin Postural Assessment scale. Lateral and posterior views will be assessed (0 = absent, 1 = mild, 2 = moderate, 3 = severe) and posture score will be determined as excellent (0-2), very good (3-4), good (5-7), fair (8-11) and poor (>12).

  4. Qol

    Time frame: 10 minutes

    Quality of life will be evaluated using Nottingham Health Profile

  5. Cognitive function

    Time frame: 5 minutes

    Cognitive function will be evaluated using Standardised Mini-Mental State Examination

  6. Fatigue

    Time frame: 5 minutes

    Fatigue will be evaluated using Multidimensional Assessment of Fatigue scale

  7. Physical activity

    Time frame: 5 minutes

    Physical activity level will be evaluated using International Physical Activity Questionnaire-Short Form

  8. Endothelial function

    Time frame: 10 minutes

    Endothelial function will be evaluated using echocardiography. After a resting baseline Brachial artery diameter will be recorded, the cuff used in blood pressure measurement will be inflated 25-50 mmHg above the systolic blood pressure value and maintaining that pressure for 5 min. The brachial artery diameter will be measured again after the cuff is deflated.

  9. Aortic stiffness

    Time frame: 10 minutes

    Aortic stiffness will be evaluated using transthoracic echocardiography. Aortic diameters can be measured by M-mode tracing of the level of 3-4 cms above the aortic valve during diastole and systole

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Official study title

The Effects of Functional Inspiratory Muscle Training on Respiratory and Peripheral Muscle Functions in Chronic Kidney Disease

Important dates

Study start
2021
Primary completion
2022
Study completion
2023
First posted
Jul 12, 2021
Registry last updated
Aug 14, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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