İnönü University Turgut Özal Medical Center General Surgery Polyclinic
Malatya, Turkey (Türkiye)
Location status: Recruiting
Location contact
Egemen Çiçek
CONTACT
NCT Number: NCT07529301
Functional status is a fundamental indicator reflecting a patient's ability to perform activities of daily living and is closely associated with early postoperative outcomes. Patients with low functional capacity are known to have an increased risk of postoperative complications, prolonged length of hospital stay, and higher mortality rates. Similarly, respiratory function plays a decisive role in the development of postoperative complications and influences early surgical outcomes. In the preoperative period, inadequate respiratory capacity and poor functional performance increase the risk of postoperative pulmonary complications and delayed recovery. Therefore, functional and respiratory assessments are regarded as integral components of the preoperative preparation process.
Early outcomes in patients undergoing colorectal cancer surgery are of critical importance in reducing mortality and morbidity. In this surgical population, advanced age, comorbidities, and diminished physical capacity may further increase the risk of postoperative complications. Accordingly, the evaluation of preoperative functional status and physiological reserve has gained increasing importance for risk stratification and perioperative management. However, studies examining the impact of functional status and respiratory parameters on early surgical outcomes in patients with colorectal cancer remain limited. Consequently, the available evidence is insufficient to establish a standardized assessment approach in clinical practice.
Moreover, objective evaluation of patients' functional and respiratory capacities in the preoperative period is essential for predicting surgical risk and planning individualized perioperative care. Determining the relationships between these parameters and early clinical outcomes may facilitate the identification of high-risk patients and contribute to the development of targeted strategies aimed at preventing postoperative complications. Findings obtained in this context are expected to provide a scientific basis for clinical decision-making and multidisciplinary patient management in individuals undergoing colorectal cancer surgery, thereby guiding clinical practice.
Interested in participating?
Request Info18 year–80 year
All sexes
Observational
Malatya, Turkey (Türkiye)
Location status: Recruiting
Egemen Çiçek
CONTACT
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Being between 18 and 80 years of age
Voluntary agreement to participate in the study
Exclusion criteria
Withdrawal from the study at the participant's own request
Elimination Criteria
Presence of a musculoskeletal condition that may prevent completion of the planned assessments
Presence of a mental impairment
History of psychiatric disorder
History of previous major surgery
Preoperative Assessments
Sociodemographic and Clinical Characteristics Sociodemographic and clinical characteristics of the patients will be recorded.
Respiratory Function Respiratory function will be measured using standard spirometric evaluation methods. Forced expiratory volume in one second (FEV₁), forced vital capacity (FVC), and peak expiratory flow (PEF) values will be recorded.
Physical Activity Level Physical activity level will be assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF).
Physical Performance Physical performance will be evaluated using the Short Physical Performance Battery (SPPB). The SPPB consists of the 4-meter gait speed test, the chair stand test, and the standing balance test. The total score will be calculated.
Ultrasonography Diaphragmatic muscle thickness will be measured using ultrasonography.
Handgrip Strength Right- and left-hand grip strength will be measured using a hand dynamometer.
Pain severity will be assessed using the McGill-Melzack Pain Questionnaire. The total pain score will be recorded.
Patient Mobility Patient mobility will be assessed using the Patient Mobility Scale.
Quality of Recovery Postoperative recovery quality will be evaluated using the Quality of Recovery-40 (QoR-40) questionnaire. The total score will be recorded.
Daily Analgesic Consumption The amount of daily analgesic use will be recorded.
Daily Flatus and Defecation The frequency and timing of daily flatus and bowel movements will be recorded.
Mobilization Daily mobilization duration, frequency, and mobilization distance (in meters) will be recorded.
Time frame: 1 year
Short Physical Performance Battery (SPPB): This scale is used to assess lower extremity physical performance. The total score ranges from 0 to 12, with higher scores indicating better physical performance.
Contact information is provided by the study sponsor or research team.
Müşerref Ebru YALÇIN
Other
The Effect of Functional Status and Respiratory Parameters on Early Postoperative Clinical Outcomes in Patients With Colorectal Cancer
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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