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Completed

NCT Number: NCT02692196

Fronto-limbic Functional Connectivity Via Real-time fMRI Neurofeedback

Real-time fMRI neurofeedback training induced volitional control of brain activity and connectivity could help individuals to gain better control over their emotions.

Completed

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Key information

Conditions

Healthy

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

School of Life Science and Technology, University of Electronic Science and Technology of China

Chengdu, Sichuan, 611731, China

About this study

In the present proof-of-concept study, investigators plan to evaluate whether real-time fMRI neurofeedback training can enable individuals to gain volitional control over their fronto-limbic circuitry. Given that this circuitry has been abundantly implicated in emotional perception and regulation this could facilitate emotional control. Suitable participants underwent fronto-limbic connectivity feedback training and sham training in a cross over design. During both trainings participants are instructed to regulate the neural indices during feedback. We expect that receiving fronto-limbic feedback enhances emotion regulation during the training.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy subjects without past or current psychiatric or neurological disorders

Exclusion criteria

  • pregnant, taking oral contraceptives

Treatment and study plan

Real-time fMRI neurofeedback from Turbo Brain voyager (TBV) 3.2

Device

Primary outcomes

  1. Neural indices of training success

    Time frame: three days

  2. Training-induced changes in emotion related processing

    Time frame: three days

    The scores of visual analogue scale assessing individuals' anxiety level will be compared between before and after training within each group as well as between twe groups after training

Sponsors and collaborators

Lead sponsor

University of Electronic Science and Technology of China

Other

Registry information

Official study title

Voluntary Regulation of Fronto-limbic Functional Connectivity: A Proof-of-concept Real-time fMRI Study

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
Feb 25, 2016
Registry last updated
Nov 8, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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