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Completed

NCT Number: NCT01550120

Free Fatty Acids: Threshold Repeatability Study

This study seeks to determine if non-esterified fatty acid (NEFA) taste detection thresholds change with repeated testing. Threshold testing for NEFA taste has been reported by a number of laboratories, including our own; however, these studies have reported data for only one testing occasion. The investigators seek to conduct repeated testing to measure the test-retest reliability of these methods. The investigators believe that with repeated exposure to NEFA, a person's sensitivity increases. The investigators are also testing the efficiency of testing by two methods (forced-choice ascending trial versus staircase). Additionally, the association between taste responses, diet and BMI will be explored.

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Key information

Conditions

Taste, Non-esterified Fatty Acids Hypersensitivity Immune System Diseases Platelet Glycoprotein IV Deficiency

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Purdue University

West Lafayette, Indiana, 47907, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-55 years old
  • in good health
  • available for three months

Exclusion criteria

Treatment and study plan

Primary outcomes

  1. Non-esterified fatty acid detection thresholds in humans

    Time frame: 6 months

  2. BMI

    Time frame: Baseline

Secondary outcomes

  1. Habitual fat intake

    Time frame: Baseline

    Block Rapid Dietary Fat Screener will be used as well as the ASA-24.

  2. testing method

    Time frame: 6 months

    Comparison of time to maximum sensitivity by participants based on forced-choice versus staircase stimulus presentation techniques.

  3. hunger

    Time frame: each visit

    Visual analog scale

Sponsors and collaborators

Lead sponsor

Purdue University

Other

Registry information

Important dates

Study start
2012
Primary completion
2013
Study completion
2013
First posted
Mar 9, 2012
Registry last updated
Nov 25, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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