Fragility Fracture Liaison Service and Anti-osteoporosis Medication Monitoring Service Study

Background:The Asia Fracture Gap Taiwan Study (AFGTS) showed that among fragility fracture sufferers, only 1/4 of them underwent bone mineral density (BMD) tests and 1/3 of them received treatments for osteoporosis. Secondary fragility fracture prevention services are needed to improve the care gaps. In addition, one-year adherence to oral anti-osteoporosis medication (AOMs) was only about 30%. In recent years, efforts have been made to change the delivery of these medications from oral form to injection form every, 3, 6 or 12 months to increase adherence. However, both patients and providers are sometimes confused about the multiple choices. Also, patients may receive extra medications if providers did not keep tract of their previous AOM uses or patients may changes providers. There were urgent needs to provide AOM monitoring and management services to improve cares.

. Aims: (1) to Establish the FLS services at the National Taiwan University Hospital Jinshan Branch. (2) To establish a anti-osteoporosis medication management service at Jinshan Branch.

Method: The FMS was designed following the 13 'Capture the Fracture Best Practice Standards'. The National Taiwan University Hospital (NTUH) institutional review board approved the study in Aug., 2015. Patients were eligible to be enrolled into the FMS part of the study if they had

• Age >=50 and one of the below
• New hip fracture in orthopedic ward
• Newly identified radiographic vertebral fractures from plan films in geriatric ward or clinical vertebral fractures in outpatient clinics
• Newly prescribed with AOMs
• Recent change of AOMs
• Poor adherence to AOMs
• Participating physicians feel that the service will benefit the patient in overall osteoporosis and medication managements.

Exclusion criteria

• Life expectancy less than 2 years or can't be assessed for communication problems
• Atypical fractures
• Patient in other medication clinical trials
• Unwilling to accept the assessment and treatment

Osteoporosis-related assessments, treatments, consultations on diet, medications, exercise, fall prevention were given mainly by care managers. A system is set up to remind patients to take their medications at home or to return to clinic for regular injections of medications. Follow up assessments included adherence to education instructions, medications, fall and fracture incidences. During the whole study period, we planed to enroll 200 patients. Each patient would be assessed at baseline, and every 4 months last for two years.

Anticipated results:

Establish Osteoporosis-related patient database combined with NTUH Participating physicians and care managers will learn new skills in managing osteoporosis patients.

Enhance adherence to AOMs The results published in the International Osteoporosis Conferences

Inclusion criteria

• Age >=50 and one of the below
• New hip fracture in orthopedic ward
• Newly identified radiographic vertebral fractures from plan films in geriatric ward or clinical vertebral fractures in outpatient clinics
• Newly prescribed with AOMs
• Recent change of AOMs
• Poor adherence to AOMs
• Participating physicians feel that the service will benefit the patient in overall osteoporosis and medication managements.

Exclusion criteria

• Life expectancy less than 2 years or can't be assessed for communication problems
• Atypical fractures
• Patient in other medication clinical trials
• Unwilling to accept the assessment and treatment