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Completed

NCT Number: NCT05639582

Fractal Analysis Method in Periodontal Disease

In this study, the effects of periodontal disease on alveolar bone were investigated using fractal analysis method.

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Key information

Conditions

Periodontal Diseases Mouth Diseases Periodontitis Stomatognathic Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Necmettin Erbakan University

Konya, Turkey (Türkiye)

About this study

Background: It is very difficult to objectively evaluate the negative changes in bone structure due to periodontitis. The present study was aimed to evaluate the trabecular bone changes between healthy individuals and periodontitis patients by fractal dimension analysis on digital panoramic radiographs.

Method: The study included 50 periodontally healthy individuals (control group), 50 individuals with Stage 1 periodontitis (S1-P group), 50 individuals with Stage 2 periodontitis (S2-P), and 50 individuals with Stage 3 periodontitis (S3-P), a total of 200 individuals were included. The fractal dimension (FD) value of the trabecular bone in the interproximal space between mandibular first molar and second premolar tooth roots was evaluated using Image J program. The mean fractal dimension values of the two regions were calculated by box counting method.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-65 years old
  • Getting a diagnosis of stage 1,2 and 3 periodontitis
  • Be diagnosed as periodontally healthy
  • Have no barriers to obtaining radiographs
  • Not having any systemic disease that may affect periodontal status
  • Not smoking and alcohol use
  • Volunteer to participate in the study

Exclusion criteria

  • Those who use drugs that can affect bone metabolism
  • Radiographs with poor diagnostic quality
  • Root canal treatment or teeth with periapical lesions in the area of interest
  • Individuals who have suffered a fracture or trauma that affects the anatomy or integrity

Treatment and study plan

fractal analysis

Other

fractal analysis is a method that numerically expresses bone changes.

Primary outcomes

  1. Evaluation of the effect of periodontal disease on alveolar bone by fractal analysis

    Time frame: baseline

    Fractal dimension evaluation can give an objective result about the effect of periodontal disease on alveoler bone, since it shows changes in bone trabeculation numerically.

Secondary outcomes

  1. Probing pocket depth

    Time frame: baseline

    Probing pocket depth(PPD) was measured for determining the severity of the disease and clinical outcome. High probing pocket depth shows more severe periodontal disease.

  2. gingival index

    Time frame: baseline

    The differences in gingival index scores between periodontally healthy and periodontitis.The gingival index was recorded for determining and classifying gingival status. The Gingival İndex(GI) scores each site on a 0 to 3 scale with 0 being normal and 3 being severe inflammation characterized by edema, redness, swelling and spontaneous bleeding.

  3. plaque index

    Time frame: baseline

    The differences in plaque index scores between periodontally healthy and periodontitis. Plaque index(PI) was recorded for determining and classifying oral hygiene status. The plaque index(PI) scores each site on a 0 to 3 scale with 0 being no plaque in the gingival area and 3 abundance of soft matter within the gingival pocket and/or on the gingival margin and adjacent tooth surface.

Sponsors and collaborators

Lead sponsor

Necmettin Erbakan University

Other

Registry information

Official study title

Evaluation of Trabecular Bone Changes in Individuals With Periodontal Disease Using Fractal Analysis

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Dec 6, 2022
Registry last updated
Dec 8, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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