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Completed

NCT Number: NCT03670459

Forty Five Patients With Multiple Sclerosis Recieved Vestibular Rehabilitation and Balance Training

Patients with multiple sclerosis (MS) might develop dizziness or vertigo as a first manifestation or during the course of the illness. Many patients with MS experience chronic or intermittent dizziness. Acute symptoms of dizziness or vertigo in MS fall into two categories; acute vestibular syndrome (AVS) and positional vertigo.

Vestibular disorder due to MS decreases whole body dynamic postural control and causes many functional limitations as limitations in ambulation, dynamic balance and trunk control and that decreases the quality of life.

Vestibular dysfunction has long been recognized as causing some of the most common symptoms in MS, true vertigo is found at presentation in up to 17% of patients, several recent reports have suggested that vestibular symptoms develop early in the disease process. Vestibular Rehabilitation has been shown to be effective in reducing symptoms and improving function for patients with vestibular disorders. The goal of vestibular rehabilitation is to promote the central nervous system compensation through exercise-based strategies.

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Key information

Conditions

Neurologic Disorder Nervous System Diseases

Age range

35 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

October 6 University

Giza, 12511, Egypt

About this study

The purposes of the study were to:

  • Measure the effect of Cawthorne Cooksey Exercises on trunk kinetics and velocity of gait in patient with MS.
  • Measure the effect of vestibular habituation on trunk kinetics and velocity of gait in patient with MS.
  • Determine which type of vestibular exercises had more effect on the rehabilitation of patients with MS Cawthorne Cooksey or vestibular habituation?
  • Determine if there was a correlation between the improvement in trunk kinetics and velocity of gait in patients with MS.

Forty five patients with multiple sclerosis were selected from the Out Patient Clinics of Neurology and Internal Medicine in Kasr Al- Aini Hospitals, Out Patient Clinic of Neurology, Faculty of Physical Therapy, Cairo University and 6th of October central hospital.

The selected patients were divided into three equal groups:

  • Patients in G1 will receive traditional physical therapy program (balance training) for twelve sessions; day after day
  • Patients in G2 will receive Cawthorne Cooksey Exercises in addition to traditional physical therapy program for twelve sessions; day after day.
  • Patients in G3 will receive vestibular habituation exercises in addition to traditional physical therapy program for twelve sessions; day after day.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All the Patients in this study will be referred from the neurologist and will be diagnosed as relapsing-remitting multiple sclerosis in the form of hemiparesis with muscle tone of 1,1+ modified Ashworth scale.
  • The diagnosis will be confirmed by MRI or CT scan and all the patients will follow the neurological examination.
  • Forty five female patients ages will range from 35-55 years.
  • All selected patients with central vertigo (central vestibular disorder) according to Dix Hallpike test (Cohen, 2004)
  • The Degree of disability of multiple sclerosis will be from 2 - 2.5 (according to expanded disability status scale (EDSS)) (Kaufman et al, 2000)
  • All the selected patients will have grade 3 group muscle test of lower limb muscles.
  • All the selected patients will have scored 27-30 in mini-mental state examination (Crum et al, 1993)
  • Patients who are selected in the study will be ambulant.
  • Patients will be medically stable.

Exclusion criteria

  • Patients with musculoskeletal deformity.
  • Patients with diabetes mellitus.
  • Patients with psychological disturbance or seizures.
  • Patients with visual or impairment.
  • Patients with inner ear disorders
  • Patients with other neurological disorders such as cerebellar lesion

Treatment and study plan

Cawthorne Cooksey Exercises

Other

Eye movements and head movements

Vestibular Habituation Exercises

Other

Move from a sitting position to flat on the back

Balance Exercises

Other

Weight Shift Forward and Back

Primary outcomes

  1. Isokinetic dynamometer

    Time frame: up to 30 days

    Assessment of trunk kinetics

Sponsors and collaborators

Lead sponsor

October 6 University

Other

Registry information

Official study title

Cawthorne Cooksey Versus Vestibular Habituation Exercises on Trunk Kinetics and Velocity of Gait in Patients With Multiple Sclerosis

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Sep 13, 2018
Registry last updated
Sep 13, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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