Focal Cortical Atrophy After Myocardial Internal Capsule

Twenty-two patients with ischemic stroke, subcortical, involving the internal capsule, will be included.

Each patient will be compared to himself, on day zero to ten and three months.

An MRI will be performed between day zero and ten, then three months of infarction sequences with traditional threeD enabling acquisition and tractography and The measurement of cortical thickness is in mm The measurement of fractional anisotropy of the pyramidal tract A clinical evaluation will be done between Day zero and Day ten then three months, using a neurological score (NIHSS), a score of functional disability (Rankin) and more analytical and sensitive tests such as dynamometer, the Finger Tapping test and test new plugs.

Inclusion criteria

• Patients of 18 to 90 years old.
• Subcortical stroke
• Achievement of the internal capsule, according to MRI
• Ability to perform MRI within 10 days after the onset of symptoms
• NIHSS over or equal 2 and < 20
• Rankin Score over or equal 1 and ≤ 5
• Written informed consent after information about the protocol, from patients or reliable person if patient is in incapacity to sign
• Affiliation to a social security scheme

Exclusion criteria

• Pregnant or nursing women
• Other cerebral lesion, concomitant or preexisting
• Concomitant disease causing unfavorable prognosis within 3 months after inclusion
• pre-existing psychiatric illness
• Alcoholism or other chronic intoxication
• Cortical localization of the infarction
• Patient in a coma, who cannot be examined and evaluated
• Patient intubated, ventilated, sedated
• Cerebral hemorrhage, intra-parenchymal and / or subarachnoid
• Persons protected by law (guardianship, curators and judicial protection)
• Contraindications to magnetic resonance examination: pacemaker, metal implants, neurostimulators, Clips neurosurgical wire sutures, staples, metal heart valves, ventricular bypass valve, metal workers, foreign eye, shrapnel, bullet , cochlear implants