Fluid vs Weight 24 Hour Balance | Clinical Trial

Key information

Conditions

Weight Bias Behavior Body Weight Body Weight Changes Fluid Accumulation Fluid Balance Pathological Conditions, Signs and Symptoms Prejudice Signs and Symptoms Social Behavior Weight Change Weight Prejudice

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

The daily fluid balance will be compared to 24hour weight change in critical care patients. The design will be prospective observational study. The data will be gathered using Linet automatic built in weight in Linet beds and for fluid balance will be used standard nurse charting method. The main outcome will be limit of agreement between daily fluid change and 24hour weight change.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

adult (age ≥ 18 years) patients admitted to intensive care unit.

Exclusion criteria

age <18 years
pregnancy
inability to obtain standardized daily body weight using the ICU bed scale
incomplete 24-hour fluid balance data preventing calculation of cumulative balance
absence of an indwelling urinary catheter, extracorporeal life support (ECMO) or other extracorporeal circulation
open abdomen
open chest
lavage or irrigation procedures during the assessment interval
surgery during the assessment
massive bleeding
diarrhoea during the assessment period
massive transfusion protocol during the 24-hour interval and ICU stay shorter than 24 hours.

Treatment and study plan

Daily Weight and fluid balance change

Other

In all enrolled patients, both 24-hour body weight change and cumulative 24-hour net fluid balance will be assessed over identical 24-hour intervals by nursing personnel. Fluid balance will be recorded using a standardized 24-hour fluid balance chart and calculated as the difference between total fluid intake and urine output and fluid output to drains. Body weight measurement will be performed once daily. Body weight will be measured using the integrated weighing system of the ICU bed.

Primary outcomes

Agreement between 24hour fluid balance and daily weight change

Time frame: 24 hours from enrollment

The primary objective of the study is to assess the agreement between changes in body weight and cumulative 24-hour fluid balance over identical time intervals in ICU patients.

Sponsors and collaborators

Lead sponsor

Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.

Other

Registry information

Official study title

More Than a Number: Why Daily Fluid Balance Alone Should Not Guide Clinical Decision-Making in the ICU: A Prospective Observational Study

Acronym: Bilance24

Important dates

Study start: 2026
Primary completion: 2026
Study completion: 2026
First posted: Mar 16, 2026
Registry last updated: Mar 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed