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OpenTrials
Completed

NCT Number: NCT01928108

Fluid Intake Application to Reduce Kidney Stone Risks

The purpose of this investigation is to prospectively evaluate the benefit of different methods of educating patients regarding their fluid intake through a readily available daily cellular phone application to improve overall urine output and reduce risk factors for stone recurrence.

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Key information

About this study

The prevalence of kidney stone disease in the United States is increasing. Recurrence of kidney stone disease has been reported as high as 50% at five years. Urine supersaturation is a predominant factor in the formation of crystallization and stone disease and is dependent on fluid volume. High fluid consumption that dilutes the urine has been shown both in vitro and in clinical studies to reduce the tendency for stone crystallization as well as effectively decrease stone recurrence. As a result, water intake greater than two liters per day is a common initial therapy for prevention of stone disease. However, studies have shown that despite physician counseling most patients are only able to modestly increase their urine volume through fluid intake. This finding may be due to a discrepancy in patient perception of their actual fluid intake and resulting urine volume. The purpose of this investigation is to prospectively evaluate the benefit of different methods of educating patient regarding their fluid intake through a readily available daily cellular phone application to improve overall urine output and reduce risk factors for stone recurrence.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients ≥ 18 years old
  • Seen in urology or nephrology clinic at UNC with a diagnosis of kidney stone
  • Prior 24-hour urine result with volume less than 2 to 2.5 liters

Exclusion criteria

  • Patient without cellular phone capable of utilizing Android / Apple application
  • Patient already using some form of monitoring fluid intake / volume
  • Inability to take fluid by mouth
  • Patient with urinary diversion, chronic diarrhea, bowel diversion or other forms of excessive fluid loss
  • Inability to obtain informed consent
  • Non-English speaking

Treatment and study plan

iPhone Application

Behavioral

The iPhone application "waterlogged" will be used by participants using and iPhone cellular device. This application will be used to track daily fluid intake for 1 week.

Android Application

Behavioral

The Android application "water my body" will be used by participants using an Android cellular device. This application will be used to track daily fluid intake for 1 week.

Primary outcomes

  1. 24-hour urine volume

    Time frame: 7-10 days from baseline

Secondary outcomes

  1. Actual 24-hour urine volume vs. patient perceived urine volume

    Time frame: 7-10 days from baseline

  2. Ease and interest in monitoring fluid intake based on survey data

    Time frame: 7-10 days from baseline

Other outcomes

  1. 24-hour urine volume for study participants vs. urine volume for retrospective cohort of previously treated kidney stone patients

    Time frame: 7-10 days from baseline

Sponsors and collaborators

Lead sponsor

University of North Carolina, Chapel Hill

Other

Registry information

Official study title

Do Different Methods of Educating Patients Regarding Fluid Intake Reduce Kidney Stone Risks?

Important dates

Study start
2013
Primary completion
2017
Study completion
2017
First posted
Aug 23, 2013
Registry last updated
Mar 28, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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