Fluid Balance and Clinical Outcomes

This study is about investigating the relationship of postoperative fluid balance, inflammation and acute kidney injury. This is a non-interventional study (no drug administration). The investigators will collect baseline demographic data, postoperative fluid balance status by Intake-output data, follow routine labs and collect 1 blood sample (0.5ml) with morning lab draws on day 1 and 5ml urine samples on day 1 and 2.

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Key information

Conditions

Fluid Balance Acute Kidney Injury Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Inflammatory Mediators Input and Output Kidney Diseases Male Urogenital Diseases Mortality Renal Insufficiency Urogenital Diseases Urologic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Shands Hospital, University of Florida

Gainesville, Florida, 32610, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age 18 years or older, and
Undergoing elective cardiothoracic surgery(s), alone or in combination with other procedures/surgery(s): thoracic aortic aneurysm, cardiac valves, coronary artery bypass grafting, abdominal thoracic aneurysm, and other cardiovascular surgery.

Exclusion criteria

Pregnancy
History of any organ transplant
Preoperative intra-aortic balloon pump (IABP)
Current use of natriuretic peptides
ESRD patients on dialysis
Estimated GFR < 30ml/min using MDRD equation.

Sponsors and collaborators

Lead sponsor

University of Florida

Other

Registry information

Official study title

Investigation of the Effect of Post-operative Fluid Balance on Inflammatory Mediators in Patients Undergoing Cardiovascular Surgery

Important dates

Study start: 2010
Primary completion: 2011
Study completion: 2011
First posted: Jul 23, 2010
Registry last updated: Sep 21, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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