Ankara Training and Research Hospital
Ankara, 06530, Turkey (Türkiye)
NCT Number: NCT07639398
Suspension laryngoscopy presents significant challenges for airway management due to the need to maintain adequate ventilation while providing optimal surgical exposure. Flow-controlled ventilation (FCV) is a novel ventilation mode that delivers constant inspiratory and expiratory flow using a narrow-lumen, cuffed endotracheal tube, potentially improving ventilation efficiency in shared-airway surgeries.
This prospective observational study aims to compare flow-controlled ventilation and conventional volume-controlled ventilation in patients undergoing elective suspension laryngoscopy. Respiratory mechanics, hemodynamic parameters, perioperative pulmonary function, and procedure-related complications will be evaluated to assess the feasibility and clinical performance of FCV in this surgical setting.
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Notify Me18 year–65 year
All sexes
Observational
Ankara, 06530, Turkey (Türkiye)
Suspension laryngoscopy is a shared-airway surgical procedure that requires optimal visualization of the operative field while maintaining adequate ventilation and oxygenation. Conventional ventilation strategies may be associated with increased airway pressures and limited surgical exposure due to the use of standard endotracheal tubes. Flow-controlled ventilation (FCV) is a ventilation mode characterized by constant inspiratory and expiratory flow, which may offer advantages in procedures requiring a narrow airway device.
This prospective, non-randomized, observational comparative study evaluates adult patients undergoing elective suspension laryngoscopy. The choice of ventilation strategy-flow-controlled ventilation or conventional volume-controlled ventilation-was based on the attending anesthesiologist's clinical preference, reflecting routine clinical practice. All patients provided written informed consent prior to participation.
In both groups, standardized anesthetic management was applied, and ventilation parameters were adjusted to maintain normocapnia and adequate oxygenation. Intraoperative respiratory mechanics, including airway pressures and lung compliance, were recorded at predefined intervals. Hemodynamic parameters were monitored throughout the procedure. Pulmonary function tests were performed preoperatively and postoperatively using a portable spirometry device. Perioperative complications were documented.
The primary objective of this study is to compare intraoperative respiratory mechanics between flow-controlled and volume-controlled ventilation during suspension laryngoscopy. Secondary objectives include the assessment of perioperative hemodynamic parameters, changes in pulmonary function, and procedure-related complications.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Adult patients aged 18 to 65 years
Exclusion criteria
- Severe cardiac, pulmonary, hepatic, or renal disease
Time frame: During surgery with 10 minute intervals
Intraoperative peak airway pressure (cmH2O) measured at predefined time intervals during suspension laryngoscopy.
Time frame: Intraoperative period during suspension laryngoscopy with 10 minute intervals.
Respiratory system compliance (mL/cmH2O) measured at predefined intraoperative time intervals.
Time frame: Intraoperative period during suspension laryngoscopy with 10 minute intervals
End-tidal carbon dioxide levels (mmHg) measured during suspension laryngoscopy.
Time frame: Intraoperative period during suspension laryngoscopy with 10 minute intervals.
Peripheral oxygen saturation (%) measured during suspension laryngoscopy.
Time frame: 30 minutes before surgery and 12 hours after surgery
Preoperative and postoperative forced expiratory volume in one second (liter) measured using pulmonary function testing.
Time frame: 30 minutes before surgery and 12 hours after surgery
Preoperative and postoperative forced vital capacity (liter) measured using pulmonary function testing.
Ankara Training and Research Hospital
Other
Comparison of Flow-Controlled Ventilation and Volume-Controlled Ventilation on Respiratory Mechanics During Suspension Laryngoscopy: A Prospective Observational Study
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