Duke University Health System
Durham, North Carolina, 27705, United States
Location status: Recruiting
NCT Number: NCT07348614
The purpose of this study is to determine if changing the type of anesthesia improves the outcomes of manipulation and pain control after the procedure. The study will compare a spinal anesthesia with a general anesthesia, to see if there is a better outcome from either anesthesia type.
Interested in participating?
Request Info18 year–75 year
All sexes
Interventional
Phase 4
Durham, North Carolina, 27705, United States
Location status: Recruiting
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion:
Exclusion:
(NSAIDs and acetaminophen)
Administration of spinal anesthesia for knee manipulation.
Administration of general anesthesia for knee manipulation.
Patients undergoing general anesthesia will receive an induction dose of propofol that will be titrated to effect, and airway support as needed until the patient is appropriately anesthetized for the procedure as determined by the anesthesia and surgical care teams.
Patients undergoing spinal anesthesia will receive a spinal injection under standard aseptic technique, with 45mg chloroprocaine.
Time frame: At time of procedure completion
Time frame: Baseline, 24 hours, 48 hours, 72 hours post-procedure
Participants will be asked to rate pain on a scale of 0-10 with 0 being no pain and 10 being the worst possible pain.
Time frame: Day 3
Duke University
Other
Flex Appeal: A Prospective Randomized Controlled Trial Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia (MUA)
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.