CHU de Clermont-Ferrand
Clermont-Ferrand, 63000, France
NCT Number: NCT05188755
Regular physical activity (PA) is associated with maintaining body composition, increased cardiorespiratory capacity, muscle mass and bone mineral density. In the event of a cancer, the development of physical capacities and metabolism may therefore be disturbed by cancer, these associated treatments (chemotherapy, radiotherapy and hematopoietic stem cell transplantation) but also undernutrition and the reduction in physical activity or even a sedentary lifestyle.
Although the benefits of PA in oncology are now well identified for adult populations, studies are still rare in the population of children, adolescents and young adults, and the results are still difficult to generalize. As a result, there is no recommendation on the practice of physical activity in pediatric oncology or adolescents and young adults and the levels of physical activity of cured patients remain lower than those of the general population.
Fitness is a marker of health in adults as well as in adolescents. Physical condition is a set of components such as cardiorespiratory capacity (transport and use of O2), body composition (distribution of bone, muscle and fat masses) and muscle function (strength, power, fatigue, energy metabolism) .
The investigators hypothesize that, compared to young adults, recovered from lymphoma are expected to exhibit impaired physical condition, due to physical deconditioning.
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Notify Me18 year–25 year
All sexes
Interventional
Not applicable
Clermont-Ferrand, 63000, France
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Other names: cardiac output, body composition, assessment of physical capacity, blood test, accelerometry, peripheral quantitative computed tomography
Time frame: day at 11:30 am during one day
maximum rate of lipid oxidation (in mg/ml)
Time frame: at 08:00 am in fasted condition during one day
energy expenditure at rest in kcal.
Time frame: at 07:30 am in fasted condition during one day
blood value of insulin in pmol/L
Time frame: at 07:30 am in fasted condition during one day
blood N-terminal pro-B natriuretic peptide level in g/L
Time frame: at 07:30 am in fasted condition during one day
blood troponin level in g/L
Time frame: at 07:30 am in fasted condition during one day
blood lipids level in g/L
Time frame: at 07:30 am in fasted condition during one day
blood glucose level in g/L
Time frame: at 07:30 am during one day
percentage of fat
Time frame: at 07:30 am during one day
percentage of lean mass
Time frame: at 11:30 am during one day
Systolic Ejection Volume in mL evaluated at rest and during submaximal exercise
Time frame: at 10:45 am during one day
Cross-sectional area of thigh muscles and intermuscular adipose tissue were assessed for muscle at 40% of the length between the greater trochanter and the mid-patella of the right leg
Time frame: at 08:45 am during one day
3 min step-test (number of ascent / descent step)
Time frame: at 08:45 am during one day
chair test (time in second held in position)
Time frame: from day 2 to day 5
daily energy expenditure (in Kcal)
Time frame: from day 2 to day 5
total sedentary time (in min) evaluated by accelerometer for 4 days
University Hospital, Clermont-Ferrand
Other
Fitness Assessment in Young Adults Recovered From Lymphoma or Hodgkin's Disease
Acronym: CUPCAKE
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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