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Completed

NCT Number: NCT03155659

Fish, Polyunsaturated Fatty Acids Intake and Mortality

Data linking fish, polyunsaturated fatty acids intake and mortality are lacking and conflicting. We aim to use data from the China Health and Nutrition Survey (CHNS) and National Health and Nutrition Examination Survey (NHANES) to investigate the associations of fish and polyunsaturated fatty acids (PUFA) intake with mortality in Chinese and US populations. The study findings will be informative for addressing the role of fish and specific PUFA in human health and improve basis for dietary recommendations.

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Key information

Conditions

Polyunsaturated Fatty Acids Mortality

Age range

20 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

Data from the China Health and Nutrition Survey (CHNS, from 1989 to 2011) and National Health and Nutrition Examination Survey (NHANES), including NHANES III conducted in 1988-1994 and continuous NHANES 1999-2010 were used to investigate the associations of fish and polyunsaturated fatty acids intake with mortality.The following variables were used:

  • Demographics: age, sex, race/ethnicity, residence
  • Socioeconomic variables: education, marital status,
  • Dietary variables: Intakes of fish, polyunsaturated fatty acids, total energy, vegetables, fruits, red meat and saturated fat
  • Clinical assessments: hypertension, diabetes, cancer, cardiovascular disease (CVD), family history of CVD

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged ≥20 with complete data on diet and follow-up time

Exclusion criteria

  • Missing information for mortality
  • Cardiovascular disease
  • Cancer

Treatment and study plan

Primary outcomes

  1. Total Mortality

    Time frame: From baseline until death or censoring on 31 December 2011, whichever came first, assessed up to an average of 10 years

    Total Mortality from All Causes

Secondary outcomes

  1. Cause-specific mortality

    Time frame: From baseline until death or censoring on 31 December 2011, whichever came first, assessed up to an average of 10 years

    Cause-specific mortality from diseases

Sponsors and collaborators

Lead sponsor

Zhejiang University

Other

Collaborators

  • National Institute of Health and Nutrition

Registry information

Official study title

Fish, Polyunsaturated Fatty Acids Intake and Mortality: Analysis of CHNS and NHANES

Important dates

Study start
1989
Primary completion
2011
Study completion
2012
First posted
May 16, 2017
Registry last updated
Mar 15, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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