NutrInvest - Institut Pasteur de Lille
Lille, Nord, 59019, France
NCT Number: NCT03872297
Fish collagen hydrolysates or peptides orally administered have been investigated in recent clinical trials in human health. These peptides have been evaluated in various biological and medical fields including skin aging, osteoarticular apparatus, muscle and more recently in energy metabolism in both animals and humans.
However, very few studies investigated the effect of fish collagen peptides on weight, body composition or glycemic response. Recently, it has been shown that the consumption of fish collagen peptides (Naticol®) limits weight gain and increase in fat mass in a mouse model made obese by a hyperlipidic diet. Since these results have never been observed in humans, this pilot study proposes to answer this question.
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Notify Me18 year–60 year
Male
Interventional
Not applicable
Lille, Nord, 59019, France
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Consumption of a non active food complement during 3 months.
Tests performed :
Consumption of the active food complement during 3 months containing Naticol.
Tests performed :
Time frame: 0 and 3 months
Weight is expressed in kilograms
Time frame: 0 and 3 months
Fat mass is expressed in kg and percent, muscle mass in kg and percent.
Time frame: 0 and 3 months
Data are expressed in centimeters
Time frame: 0 and 3 months
Total cholesterol, HDL cholesterol, LDL cholesterol, and Triglycerides. Data are expressed in g/L and in mmol/L
Time frame: 0 and 3 months
Data are expressed in g/L and mmo/L
Time frame: 0 and 3 months
Data are expressed in μU/ml
Time frame: 0 and 3 months
This index indicates the insulin resistance and was calculated as follow : HOMA [(glycémie mmol/l X insulinémie μU/ml) à jeun / 22,5]
Time frame: 0 and 3 months
Score obtained via Ricci and Gagnon questionnaire. The questionnaire contains 9 questions ; score could be between 9 and 45 points.
Time frame: 0 and 3 months
Assay for TNFalpha, IL-1beta and IL-6 in plasma
Time frame: 0 and 3 months
Rate comparison of different bacteria families
centimeters
Time frame: 0 and 3 months
kg/m²
Institut Pasteur de Lille
Other
Effect of a Fish Collagen Peptide Food Supplement on the Weight and Body Composition of Healthy Volunteers in Overweight
Acronym: NATICOL
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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