Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07084155

Final Prototype Refinement of Adaptive Cell Phone Support

The goal of this feasibility pilot trial is to finalize the design of a mobile health intervention for promoting medication adherence in a population of adolescents and young adults with chronic health conditions. The main question[s] it aims to answer are:

1. Is the final version of the intervention sufficiently feasible, usable, and acceptable for evaluation in a randomized clinical trial? 2. Do participants show improvements in medication adherence during their field testing of the intervention?

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Medication Adherence Behavior Health Behavior Patient Acceptance of Health Care Patient Compliance Treatment Adherence and Compliance

Age range

15 year–20 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Children's Hospital Los Angeles

Los Angeles, California, 90027, United States

Location status: Recruiting

Location contact

Caitlin S Sayegh, PhD

CONTACT

[email protected]

323-361-7748

About this study

Adolescents with chronic health conditions will be asked to try the intervention for three weeks and give feedback to refine the structure and content in preparation for a future randomized trial of the finalized version of the intervention. Plan to enroll 35 participants in this single arm feasibility/usability trial.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children's Hospital Los Angeles patient
  • between 15-20 years old at enrollment
  • taking at least one oral medication per day for a chronic health condition
  • English speaking
  • demonstrating sufficient cognitive capacity to engage in the assent/consent process and study procedures

There is no exclusion criteria.

Treatment and study plan

Adaptive Cell Phone Support

Behavioral

Mobile health adherence promotion based on the supportive accountability model

Primary outcomes

  1. Total scores on the theoretical framework of acceptability questionnaire

    Time frame: Baseline to 3 weeks

    Higher scores indicate a greater "extent to which people delivering or receiving a healthcare intervention consider it to be appropriate, based on anticipated or experienced cognitive and emotional responses to the intervention"; the minimum value of this questionnaire is 7 and the maximum value is 35.

  2. Mean scores on the Mobile Health App Usability Questionnaire

    Time frame: Baseline to 3 weeks

    Higher scores indicate greater ease with which users can use technology to achieve a particular goal; the minimum value of this questionnaire is 1 and the maximum value is 7.

  3. Total scores on the Visual Analogue Scale

    Time frame: Baseline to 3 weeks

    Percentage of doses taken our of 100%; higher numbers indicate greater medication adherence. This scale presents participants with a line, marked 0 on the left and 100 on the right, and participants can drag a marker to the place on the line that best visually indicated their adherence.

Study contacts

Contact information is provided by the study sponsor or research team.

Caitlin Sayegh, PhD

CONTACT

[email protected]

323-361-7748

Sponsors and collaborators

Lead sponsor

Children's Hospital Los Angeles

Other

Collaborators

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Registry information

Official study title

Adaptive Cell Phone Support to Promote Medication Adherence Among Adolescents and Young Adults With Chronic Health Conditions

Acronym: ACPS

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Jul 24, 2025
Registry last updated
Jul 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.