FILLing Protocols for the Right Bladder Volume at the RIGHT Time (FILLRIGHT)

The cumulative duration, for each protocol, during which two conditions are met:

• Bladder volume greater than 150 ml
• Blader Sensation Scale (BSS) score ≤ 2 The BSS is a medical tool used to evaluate and quantify how a patient perceives bladder fullness. The scale typically ranges from 0 to 4 .

Each score represents what the patient feels at a specific moment:

0: No sensation - The bladder is empty, or the patient feels absolutely nothing.

• First desire to void - The patient feels the bladder is starting to fill, but it can easily be ignored for a long time.
• Normal desire to void - The usual feeling that prompts a person to go to the restroom. The urge can be postponed if the person is busy.
• Strong desire to void / Urgency - The bladder is full. The urge is strong and uncomfortable; it is becoming difficult to delay.
• Urgent / Painful desire to void - The urge is so intense that it causes discomfort, pain, or fear of leakage. The patient must go immediately.

For each protocol, the average curve of bladder volume progression will plott. A suprapubic ultrasound examination will be performed every 5 minutes during the procedure to calculate of bladder volume using the standard formula (length × width × height × 0.52).

For each protocol, the average curve of Bladder Sensation Scale (BSS) progression will plott.

The BSS is a medical tool used to evaluate and quantify how a patient perceives bladder fullness. The scale typically ranges from 0 to 4 .

Each score represents what the patient feels at a specific moment:

0: No sensation - The bladder is empty, or the patient feels absolutely nothing.

• First desire to void - The patient feels the bladder is starting to fill, but it can easily be ignored for a long time.
• Normal desire to void - The usual feeling that prompts a person to go to the restroom. The urge can be postponed if the person is busy.
• Strong desire to void / Urgency - The bladder is full. The urge is strong and uncomfortable; it is becoming difficult to delay.
• Urgent / Painful desire to void - The urge is so intense that it causes discomfort, pain, or fear of leakage. The patient must go immediately.

Correlation between filling rate (a suprapubic ultrasound examination will be performed to assess the bladder filling every 5 minutes during the procedure) and the Bladder Sensation Scale will be assessed at the same time.

Determination, for each protocol, of the minimum time required to achieve a bladder volume ≥ 150 ml in all participants (a suprapubic ultrasound examination will be performed to assess the bladder filling every 5 minutes during the procedure).

Absolute and relative difference between the actual urine volume and the ultrasound-estimated volume just before voiding at the end of the procedure, adjusted after ultrasound estimation of post-void residual urine.

Before ingestion of water, the patient should urinate band (the volumen will be measured) an an ultrasound examination will be performed to assess the residual post-void volume.

When the BSS score reaches 3, the procedure should be stopped and the patiente should urinate band (the volumen will be measured). Then a last ultrasound examination will be performed.

Cumulative acceptability score for each protocol on a scale from 1 to 10. Response to the question: "On a scale from 1 (very poor) to 10 (excellent), how would you rate the acceptability of ingesting the required hydration volume?"