Active, Not Recruiting

NCT Number: NCT01796145

Fibroscan Study in HCC

In patients with HCC undergoing therapy 1. We aim to determine the prognostic significance of liver stiffness in patients with HCC 2. We aim to determine the rate and severity of complications of treatment and its association with liver stiffness in patients with HCC

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Confirmed Diagnosis of Hepatocellular Carcinoma Child's A to C Cirrhosis Patients Who Are Scheduled to Undergo Transarterial Chemobolization, Systemic Therapy Surgery

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Clinical Oncology, Prince of Wales Hospital

Hong Kong

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Clinical diagnosis of HCC
Patients who are scheduled to undergo therapy, either TACE systemic therapy or surgery

For TACE cohort, patients undergoing first cycle TACE are eligible.
For systemic therapy cohort, patients undergoing first-line systemic therapy are eligible.
For surgery cohort, patient undergoing surgery are eligible.
Prior surgery or loco-ablative therapy (e.g. Radiofrequency ablation, microwave, percutaneous ethanol injection) is allowed
Child's A to Child's C liver function

Exclusion criteria

ECOG performance status > 2
Poorly controlled ascites

Treatment and study plan

Fibroscan

Other

Primary outcomes

Overall survival

Time frame: 3 years

Secondary outcomes

Rate and grade of treatment complications

Time frame: 2 years
Liver stiffness (kPa)

Time frame: 2 years

Sponsors and collaborators

Lead sponsor

Chinese University of Hong Kong

Other

Registry information

Official study title

A Study to Evaluate the Impact of Liver Stiffness on Treatment Outcome of Hepatocellular Carcinoma

Important dates

Study start: 2013
Primary completion: 2026
Study completion: 2027
First posted: Feb 21, 2013
Registry last updated: Nov 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.