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NCT Number: NCT07402772

Female Osteoporosis

The aim of this study is to compare the Osteoporosis Risk Assessment Tool and the Osteoporosis Self-Assessment Tool with the gold standard DEXA in determining the risk of osteoporosis in the lumbar and femoral regions in female individuals in the Turkish population, and to investigate their sensitivity and specificity in the first stage of screening for the detection of female osteoporosis.

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Key information

Conditions

Age range

50 year–75 year

Sex eligibility

Female

Study type

Observational

About this study

This study will be conducted as a single-center, retrospective study at the Physical Medicine and Rehabilitation Clinic of Kayseri City Hospital between January 2024 and January 2025. This study will include female patients aged 50-75 who underwent osteoporosis screening with DEXA at the Kayseri City Hospital FTR outpatient clinics between January 2021 and January 2024. Patient data will be obtained retrospectively from the hospital database. Sociodemographic data (age, height, weight, body mass index) and current laboratory data (complete blood count, biochemical values (fasting blood sugar, BUN, creatinine, AST, ALT, calcium, phosphorus, alkaline phosphatase, total protein, albumin, parathyroid hormone, vitamin D3, T4, TSH), and DEXA values (bone mineral density, lumbar vertebrae, and femoral neck and total femur T scores) will be recorded. The OST score will be calculated using body weight and age parameters. The ORAI score will be calculated using age, weight, and estrogen use from hospital data.

The data will be evaluated using the SPSS 24.0 software package. Descriptive statistical analyses will include calculations of mean, standard deviation, frequency, and percentages. In comparative statistics, the Student T-test or Mann Whitney U-test will be used to compare independent groups. Chi-square analysis will be applied to compare categorical variables. Pearson or Spearman correlation analyses will be applied to evaluate the relationship between variables. Both groups will be compared, and p<0.05 will be considered statistically significant.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Postmenopausal women aged 50-75
  • Patients who underwent imaging with the STRATOS DEXA device at Kayseri City Hospital

Exclusion criteria

  • Patients younger than 50 or older than 75 years of age
  • Patients with secondary osteoporosis
  • Male patients
  • Patients with uncontrolled severe comorbid conditions
  • Patients with a history of pathological fractures

Treatment and study plan

Primary outcomes

  1. Dual-energy X-ray absorptiometry (DEXA)

    Time frame: January 2021 - January 2024

    Dual-energy X-ray absorptiometry (DEXA)

  2. Osteoporosis Self-Assessment Tool (OST)

    Time frame: January 2021 - January 2024

    Osteoporosis Self-Assessment Tool (OST)

  3. Osteoporosis Risk Assessment Index (ORAI)

    Time frame: January 2021 - January 2024

    Osteoporosis Risk Assessment Index (ORAI)

Study contacts

Contact information is provided by the study sponsor or research team.

Fatma Gül Ülkü Demir, MD

CONTACT

[email protected]

+903523157700

Sponsors and collaborators

Lead sponsor

Kayseri City Hospital

Other Gov

Registry information

Official study title

Performance of the Osteoporosis Self-Assessment Tool (OST) and Osteoporosis Risk Assessment Index (ORAI) in Predicting Osteoporosis in Postmenopausal Turkish Women

Acronym: OST and ORAI

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Feb 11, 2026
Registry last updated
Feb 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.