University of Exeter
Exeter, EX1 2LT, United Kingdom
NCT Number: NCT05397418
Participating in regular physical activity has been shown to reduce the risk of developing some diseases and disabilities that can occur with ageing. Muscles naturally decline with age, and in females this appears to occur more so around the time of menopause. Time, work, family commitments and the availability of facilities have all been identified as barriers to exercise in middle age.
Increasing activity levels in middle age appears to improve muscle function and bone health. However, there is a lack of evidence in how muscle function responds to low impact resistance exercise in middle aged females.
This study aims to assess the effectiveness and the mechanisms associated with building muscle as well as the effect on quality of life in middle aged (40-60 years) females using a low impact resistance training programme.
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Notify Me40 year–60 year
Female
Interventional
Not applicable
Exeter, EX1 2LT, United Kingdom
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
12 week supervised low impact resistance training program
12 week unsupervised low impact resistance training program
Time frame: 12 weeks
Peak torque (Nm) of the shoulder and hip
Time frame: 12 weeks
Changes in fat mass and lean body mass
Time frame: 12 weeks
Changes in bone mineral density
Time frame: 12 weeks
Changes in muscle thickness
Time frame: 12 weeks
Rate of muscle protein synthesis
Time frame: 12 weeks
Changes in energy expenditure rates
Time frame: 12 weeks
Changes in sleep quality using the Pittsburgh sleep quality index (PSQI) questionnaire
Time frame: 12 weeks
Changes in self reported wellbeing measures using the Short Form Survey (SF-36)
Time frame: 12 weeks
Changes in physical activity energy expenditure as measured using an accelerometer
Time frame: 12 weeks
Changes in the rating of enjoyment of leisure time activity using the Groningen Enjoyment Questionnaire to rate enjoyment of exercise on a scale from strongly disagree to strongly agree
Time frame: 12 weeks
Balance measured using the Y-balance test
Time frame: 12 weeks
Flexibility measured using distance (cm) in zipper and sit and reach test
Time frame: 12 weeks
Changes in biochemical lipid profile
Time frame: 12 weeks
Changes in biochemical measures of HbA1c
Time frame: 12 weeks
Suitability of the exercise program as a sustainable form of unsupervised online exercise as recorded in participant exercise diaries.
University of Exeter
Other
Effectiveness of a 12-week Low Impact Resistance Training Programme on Muscle Function, Body Composition, Quality of Life and Muscle Protein Synthesis in Women Aged 40-60 Years
Acronym: FemME
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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