Feasibility Study for PANDAS

Feasibility study to obtain information through a telephone interview with parents of eligible children Once we identify the children who were less than one year of age and those between the ages of 1 and 3 that who had inguinal hernia surgery during the years of 1999-2007, we will call the parents to determine if the index patients have siblings. If so, we would also ask if there is a sibling within 3 years of the index patient's age and if they have had no exposure to anesthetics or sedatives before their third birthday. Exclusion criteria for both index patients and siblings would include gestational age at birth of < 36 weeks, any history of hospitalization, including neonatal ICU, a history of CNS, cardiac, or pulmonary diseases requiring medical treatment, or a history of subsequent surgery or exposure of anesthetics or sedatives.

Inclusion criteria

• Males or females age 0 to 1 year.
• Inguinal hernia surgery between 1/1/1999 and 12/31/2007.
• Parental/guardian permission (informed consent).

Exclusion criteria

• Gestational age < 36 weeks.
• Any history of hospitalization, including neonatal ICU.
• A history of CNS, cardiac, or pulmonary diseases requiring medical treatment.
• History of subsequent surgery or exposure to anesthetics or sedatives at less than 3 years of age.

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