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Completed

NCT Number: NCT01981200

Feasibility of Strength Training in Patients Hospitalized Due to COPD

To examine the feasibility of progressive unilateral knee-extension strength training using ankle weight cuffs in patients hospitalized due to acute exacerbation in COPD

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Key information

Conditions

COPD Chronic Disease Disease Attributes Lung Diseases Lung Diseases, Obstructive Muscle Weakness Muscular Diseases Musculoskeletal Diseases Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases Signs and Symptoms

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Nordsjællands Hospital - Frederikssund

Frederikssund, 3600, Denmark

About this study

We decided that feasibility is indicated if: 1) the absolute training loads increase progressively, 2) more than 80% of the planned training sessions are completed, and 3)if the absolute training loads do not exceed 20 kg (2 x10kg weight cuffs) for 90% of patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Have a primary diagnosis of COPD
  • Be admitted to the pulmonary ward due to an exacerbation in COPD
  • Provide informed consent to participation in the study
  • Be able to maintain an upright position on a chair
  • Be able to be guided to training and understand instructions for participating

Exclusion criteria

Patients suffering from diseases that prevents the use of wrist weights such as

  • Deep venous thrombosis (DVT)
  • Erysipelas
  • Painful edema of the limbs
  • Lack of ability to walk, habitually
  • Predicted hospital stay of less than four days as predicted by a pulmonary physician
  • Patients admitted Friday night or Saturday morning cannot be stared up within 24 hours of admittance

Treatment and study plan

Resistance training in AECOPD

Other

The patients begin training on day 1 of admittance. The training consists of knee extension performed in the sitting position on the bed with a 90 degrees of flexion of the knees. The weight cuffs are tired to the angles with a weight corresponding to 10 RM (the weight lifted 10 times). The weights and exercises are subjected to supervision on daily basis by the physiotherapist. The weight is increased after every set of training if more than 10 rep. can be performed with a given weight. Limitations to exercise is also recorded along with the degree of dyspnoea as assessed by the Borg CR10, possible oxygen supplementation and saturation is recorded before and following exercise.

Other names: Weight cuffs, Strength training, hospitalization

Primary outcomes

  1. Increase of training load during admission

    Time frame: The patients will be followed for the duration of hospital stay, an expected average of 6 days

    Change in training loads measured by the number of kilos lifted using ankle weight cuffs in 3 sets of 10 repetition maximum at the first training day to the number of kilos lifted at the last training day

Secondary outcomes

  1. Maximal isometric knee extension strength

    Time frame: The patients will be followed for the duration of hospital stay, an expected average of 6 days

    Maximal isometric knee extension strength is measured unilaterally by a fixated handheld dynamometer. The test will be performed upon admission and at the day of discharge

  2. Sit-to- stand- test

    Time frame: The patients will be followed for the duration of hospital stay, an expected average of 6 days

    The number of times the patient comes to full standing position in 30 seconds. The Sit to Stand test provides a measurement of a person's lower body (particularly quadriceps) strength. This is associated with the ability to perform lifestyle tasks such as climbing stairs, getting in and out of a vehicle or bath. The test will be performed upon admission and on the day of discharge

  3. Timed Up and Go (TUG)

    Time frame: The patients will be followed for the duration of hospital stay, an expected average of 6 days

    A test used to assess a person's mobility and requires both static and dynamic balance. The time that a person takes to rise from a chair, walk three metres, turn around, walk back to the chair, and sit Down. The test will be performed at admission and at the day of discharge

Sponsors and collaborators

Lead sponsor

Frederikssunds Hospital, Denmark

Other

Collaborators

  • Copenhagen University Hospital, Hvidovre

Registry information

Official study title

Feasibility of Progressive Knee Extension Strength Training Using Ankle Weight Cuffs in Patients Hospitalized With COPD in Acute Exacerbation

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Nov 11, 2013
Registry last updated
Feb 11, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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