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NCT Number: NCT06671847

Feasibility of At-Home Chair-Based Resistance Band Training to Improve Balance, Strength, and Bone Density in Older Adults

The purpose of this study is to determine the feasibility of implementing a 24-week at-home chair-based resistance band training intervention, to determine effectiveness of a the a 24-week at-home chair-based resistance band training intervention in improving body composition and to determine the effectiveness of a 24-week at-home chair-based resistance band training intervention in improving physical performance in adults 50 years and older, receiving care at the UT Physicians Center for Healthy Aging.

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Key information

Conditions

Age range

50 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • English-speaking
  • receive care at the UT Physician Center for Healthy Aging

Exclusion criteria

  • inability to provide informed consent on their own
  • presence of obvious signs of cognitive decline
  • a diagnosis of dementia and inability to come to the clinic for the scheduled study visits.

Treatment and study plan

THERABand resistance exercise bands

Device

The training will be performed using THERABand resistance exercise bands.Participants will be instructed to perform the exercises twice per week at home, for the 24 weeks duration. Each exercise session will entail 1 set of 15 repetitions of 9 different exercises

Primary outcomes

  1. Feasibility as assessed by the number of people who are able to follow the prescribed exercise regimen at least 50 percent of the time

    Time frame: end of study (24 weeks from baseline)

Secondary outcomes

  1. Change in body fat

    Time frame: baseline,6-months

    This will be assessed using the handheld bioelectrical impedance analysis (BIA) device (Omron HBF-510)

  2. Change in bone mineral density (BMD) of the femoral neck and lumbar spine

    Time frame: baseline, 1 year from baseline

    This will be assessed by the Dual energy x-ray absorptiometry (DXA)

  3. Handgrip strength

    Time frame: baseline

    This will be assessed using a validated handgrip dynamometer

  4. Handgrip strength

    Time frame: 1-month

    This will be assessed using a validated handgrip dynamometer

  5. Handgrip strength

    Time frame: 3-months

    This will be assessed using a validated handgrip dynamometer

  6. Handgrip strength

    Time frame: 6-months

    This will be assessed using a validated handgrip dynamometer

  7. 60-second balance as assessed by the the Zibrio Stability Pro scale

    Time frame: Baseline

    This is determined by the patient standing on the Zibrio Stability Pro Scale unassisted for one minute and will be measured on a scale of 1 to 9 with lower scores indicating higher risk of fall

  8. 60-second balance as assessed by the the Zibrio Stability Pro scale

    Time frame: 1-month

    This is determined by the patient standing on the Zibrio Stability Pro Scale unassisted for one minute and will be measured on a scale of 1 to 9 with lower scores indicating higher risk of fall

  9. 60-second balance as assessed by the the Zibrio Stability Pro scale

    Time frame: 3-months

    This is determined by the patient standing on the Zibrio Stability Pro Scale unassisted for one minute and will be measured on a scale of 1 to 9 with lower scores indicating higher risk of fall

  10. 60-second balance as assessed by the the Zibrio Stability Pro scale

    Time frame: 6-months

    This is determined by the patient standing on the Zibrio Stability Pro Scale unassisted for one minute and will be measured on a scale of 1 to 9 with lower scores indicating higher risk of fall

  11. walking gait speed

    Time frame: Baseline

    Gait speed will be assessed over a 6-meter distance measured within a private clinic space. The participant will be instructed to walk at their normal walking pace (as if they were walking throughout the house) and the distance/time will be converted to meters/second.Faster walking speed is related to reduced fall-risk, improved physical function, and greater survival .

  12. walking gait speed

    Time frame: 1-month

    Gait speed will be assessed over a 6-meter distance measured within a private clinic space. The participant will be instructed to walk at their normal walking pace (as if they were walking throughout the house) and the distance/time will be converted to meters/second.Faster walking speed is related to reduced fall-risk, improved physical function, and greater survival .

  13. walking gait speed

    Time frame: 3-months

    Gait speed will be assessed over a 6-meter distance measured within a private clinic space. The participant will be instructed to walk at their normal walking pace (as if they were walking throughout the house) and the distance/time will be converted to meters/second.Faster walking speed is related to reduced fall-risk, improved physical function, and greater survival .

  14. walking gait speed

    Time frame: 6-months

    Gait speed will be assessed over a 6-meter distance measured within a private clinic space. The participant will be instructed to walk at their normal walking pace (as if they were walking throughout the house) and the distance/time will be converted to meters/second.Faster walking speed is related to reduced fall-risk, improved physical function, and greater survival .

  15. Blood level of pro-collagen type 1 N-telopeptide (P1NP)

    Time frame: Baseline

    P1NP is a metabolic marker of bone formation, indicates status of bone loss and a stable or decreased level will be indicating improved metabolism

  16. Blood level of pro-collagen type 1 N-telopeptide (P1NP)

    Time frame: 6 months

    P1NP is a metabolic marker of bone formation, indicates status of bone loss and a stable or decreased level will be indicating improved metabolism

  17. Frailty as assessed by the Fried criteria

    Time frame: Baseline

    This consists of 5 items (unintentional weight loss, weakness [low grip strength], slowness low, self-reported exhaustion and low physical activity). Patients who meet 1or 2 of the criteria are described as pre-frail and 3 or more as frail.

  18. Frailty as assessed by the Fried criteria

    Time frame: 1-month

    This consists of 5 items (unintentional weight loss, weakness [low grip strength], slowness low, self-reported exhaustion and low physical activity). Patients who meet 1or 2 of the criteria are described as pre-frail and 3 or more as frail.

  19. Frailty as assessed by the Fried criteria

    Time frame: 3-months

    This consists of 5 items (unintentional weight loss, weakness [low grip strength], slowness low, self-reported exhaustion and low physical activity). Patients who meet 1or 2 of the criteria are described as pre-frail and 3 or more as frail.

  20. Frailty as assessed by the Fried criteria

    Time frame: 6-months

    This consists of 5 items (unintentional weight loss, weakness [low grip strength], slowness low, self-reported exhaustion and low physical activity). Patients who meet 1or 2 of the criteria are described as pre-frail and 3 or more as frail.

Study contacts

Contact information is provided by the study sponsor or research team.

Jude des Bordes, MBChB, DrPH

CONTACT

[email protected]

(713) 500-6029

Nahid Rianon, MBBS,DrPH

CONTACT

[email protected]

(713) 500-5106

Sponsors and collaborators

Lead sponsor

The University of Texas Health Science Center, Houston

Other

Registry information

Official study title

Feasibility of 24-Weeks of At-Home Chair-Based Resistance Band Training to Improve Balance, Strength, and Bone Density in Older Adults (ChaREx Study)

Acronym: ChaREx

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Nov 4, 2024
Registry last updated
Nov 4, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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