Feasibility and Tolerance Study for the Treatment of Varicose Ulcers by Cyanoacrylate Glue (ETUVVE)

Inclusion criteria

• Primary insufficiency of the great saphenous vein (GVS) by a reflux> 0.5 second from the inter-fascial saphenous trunk to the upper 1/3 of the thigh extending over the entire height of the thigh either in the saphenous compartment or in at least one extra-fascial tributary, in a standing patient, by compression of the calf
• CEAP: C6, ulcer present on a single leg whose size can be captured by a simple photograph
• Diameter of the GVS at the saphenofemoral junction ≥3 or ≤12 millimeters
• Patient affiliated or beneficiary of a social security scheme
• Patient having signed the informed consent

Exclusion criteria

• Patient with a circumferential ulcer
• Patient with ipsilateral small saphenous vein insufficiency
• Presenting a serious current pathology and / or a life expectancy of less than 5 years
• History of deep or superficial vein thrombosis in the previous 6 months
• Patient with arteriopathy obliterating of the affected lower limb, with an IPS <0.8 or> 1.3
• With post-thrombotic obstructive syndrome in the popliteal and / or femoral and / or iliac stage on the ipsilateral lower limb
• Presenting primary or post-thrombotic axial deep venous reflux on the ipsilateral lower limb
• Suspicion of non-post-thrombotic iliac compression on Doppler ultrasound
• Contraindication to the intended treatment technique
• Known allergy to cyanoacrylate glue or xylocaine
• Patient with a BMI greater than 40 (morbid obesity)
• Patient whose geographical distance is not compatible with the follow-up of the study
• Pregnant or breastfeeding woman
• Patient participating in another clinical study
• Patient linguistically or psychically unable to understand the information given, to give informed consent or to answer the study questionnaires.
• Protected patients: Adults under some guardianship or other legal protection; Hospitalized without consent