NCT Number: NCT07284004
Fatty Liver in Long Standing Cholecystectomy
This observational study aims to evaluate the association between long-term cholecystectomy and the development of metabolic dysfunction-associated fatty liver disease (MAFLD) in adult patients. The study will assess the prevalence and severity of hepatic steatosis in individuals who underwent cholecystectomy several years earlier and compare clinical, metabolic, and biochemical parameters to identify potential risk factors. The goal is to determine whether cholecystectomy contributes to metabolic alterations that increase the likelihood of MAFLD in the long term.
Trial opening soon.
Get NotifiedKey information
Age range
18 year and older
Sex eligibility
All sexes
Study type
Observational
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
-
Exclusion criteria
- Patients less than 18 years old.
- Body mass index (BMI) ≤ 25 kg/m2
- Patients with chronic renal failure.
- Patients with liver cirrhosis.
- Patients with acute liver dysfunction.
- Breast feeding and pregnancy.
- patients have done cholecystectomy less than 5 years ago.
Treatment and study plan
Primary outcomes
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Incidence and severity of metabolic dysfunction-associated fatty liver disease (MAFLD) in patients after long term follow up post cholecystectomy
Time frame: 5 years post-cholecystectomy
Secondary outcomes
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Changes in serum level of ALT in post-cholecystectomy patients
Time frame: Annually for 5 years
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
Yasmeen Ahmed Farrag Ahmed
Other
Registry information
Official study title
Metabolic Dysfunction Associated Fatty Liver Disease in Long-Term Cholecystectomy Patiens
Acronym: MAFLD-Chole St
Important dates
- Study start
- 2025
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Dec 16, 2025
- Registry last updated
- Dec 16, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.