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Completed

NCT Number: NCT05228028

Fascia Iliaca Compartment Block Versus Quadratus Lumborum Block in Total Hip Arthroplasty

Patients undergoing total hip arthroplasty are randomly assigned to two groups (fascia iliaca compartement block [FICB] group or quadratus lumborum block [QLB] group). In the FICB group, ultrasound-guided suprainguinal FICB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is performed on the ipsilateral surgical side at the end of surgery. In the QLB group, ultrasound-guided anterior QLB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is done on the ipsilateral surgical side at the end of surgery. A standardized multimodal analgesic regimen is used for postoperative pain control. The total use of opioids including patient-controlled analgesia and rescue analgesics is compared in both groups for 24 hours after surgery. The amount of opioids used is compared by conversion to oral morphine equivalent dose. Pain score at rest and movement during postoperative 24 hours, time to first request for analgesics, the incidence of side effects, patient satisfaction for pain control at postoperative 24 hours, quality of recovery at postoperative 24 hours, time to discharge readiness, and hospital length of stay are compared.

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Key information

Conditions

Nerve Block Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

19 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Seoul National University Hospital

Seoul, 03080, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients between the ages of 19 and 70 undergoing total hip arthroplasty under spinal anesthesia
  • Be able to provide written consent to participate in clinical trials, understand the procedures of this clinical trial, and be able to properly fill out patient-reported questionnaires
  • ASA physical status classification 1-2

Exclusion criteria

  • ASA physical status classification 3-4
  • Patients who are contraindicated to nerve blocks (hypersensitivity to local anesthetics, infection at the injection site, etc.)
  • Patients with chronic pain and taking pain medications, antidepressants, and anticonvulsants
  • Other major medical or psychiatric conditions that will affect response to treatment
  • Refusal of intravenous patient-controlled analgesia
  • Patients determined to be unsuitable for this clinical trial by the researchers

Treatment and study plan

fascia iliaca compartement block

Procedure

Ultrasound-guided suprainguinal FICB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is done on the ipsilateral surgical side at the end of surgery.

Other names: FICB

quadratus lumborum block

Procedure

Ultrasound-guided anterior QLB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is done on the ipsilateral surgical side at the end of surgery.

Other names: QLB

Primary outcomes

  1. Total opioids use for 24 hours

    Time frame: Over the first 24 hours after surgery

    Total dose of opioids used upto 24 hours after surgery (morphine milligram equivalents)

Secondary outcomes

  1. Postoperative pain at rest (Numeric rating scale)

    Time frame: At postoperative 4, 8, 12, 16, 20, 24 hours

    Postoperative pain at rest (Numeric rating scale; minimum 0, maximum 10, a higher score means more pain)

  2. Postoperative pain with movement (Numeric rating scale)

    Time frame: At postoperative 4, 8, 12, 16, 20, 24 hours

    Postoperative pain with movement (Numeric rating scale; minimum 0, maximum 10, a higher score means more pain)

  3. Time to first request for pain medication

    Time frame: From the end of surgery to discharge, an average of 4 days

    Time to first request for pain medication after surgery

  4. Incidence of postoperative nausea and vomiting

    Time frame: Over the first 24 hours after surgery

    Incidence of postoperative nausea and vomiting (%)

  5. Patient satisfaction score with pain control at 24 hours after surgery

    Time frame: At 24 hours after surgery

    Patient satisfaction score with pain control at 24 hours after surgery (minimum 0, maximum 10, a higher score means higher satisfaction)

  6. Quality of Recovery at 24 hours after surgery

    Time frame: At 24 hours after surgery

    Quality of Recovery at 24 hours after surgery assessed by QoR-15 questionnaire

  7. Time to discharge readiness

    Time frame: From the end of surgery to discharge, an average of 4 days

    Days of hospitalization after surgery until discharge readiness (defined as satisfying the following three criteria; (1) adequate pain control (numeric rating scale score < 4), (2) no intravenous opioid use in the past 12 hours, and (3) able to walk at least 30 m without time limit)

  8. Hospital length of stay

    Time frame: From the end of surgery to discharge, an average of 4 days

    Days of hospitalization after surgery until discharge

Sponsors and collaborators

Lead sponsor

Seoul National University Hospital

Other

Registry information

Official study title

Suprainguinal Fascia Iliaca Compartment Block Versus Anterior Quadratus Lumborum Block for Analgesia After Total Hip Arthroplasty: a Randomized Controlled Trial

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
Feb 8, 2022
Registry last updated
Dec 28, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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