Family Research Study: Metabolism of Fats and Proteins in Specific Ethnic Groups

The purpose of this study is to determine whether lipoprotein(a), also called Lp(a), is a risk factor for cardiovascular (heart) disease. Lipoproteins are tiny particles that circulate in the blood. They contain cholesterol, fat, and protein in varying amounts depending on the body's need. Higher levels of lipoproteins in the blood can cause an increased risk of heart disease.

The investigators believe that by studying the Lp(a) lipoprotein in Caucasians and African Americans, the investigators can assess for genetic variation factors related to cardiovascular (heart) disease. The investigators will be looking at 100 African-American families and 100 Caucasian families to confirm whether a higher Lp(a) level is an indicator of a higher risk for heart disease.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Healthy Cardiovascular Diseases Heart Disease Heart Diseases

Age range

6 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

UC Davis CTSC Clinical Research Center (CCRC) at Veterans Affair Medical Center

Mather, California, 95655, United States

About this study

During the study visit the research staff will ask about the medical history, perform a brief physical exam, and draw approximately 4 teaspoons of blood of each family member.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Of Caucasian or African descent
Families must have 2 natural/biological parents and 2 natural/biological offspring
6 years old or older

Exclusion criteria

Races other than African American or Caucasian
Families without 2 natural/biological parents and 2 natural/biological offspring
younger that 6 years old

Treatment and study plan

no intervention, observational study

Other

Primary outcomes

Genetic variation of Lp(a) levels in each group

Time frame: five years

Sponsors and collaborators

Lead sponsor

University of California, Davis

Other

Collaborators

National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health (NIH)

Registry information

Official study title

Regulation of Lipoprotein(a) Metabolism in Humans With Reference to Ethnicity

Important dates

Study start: 2009
Primary completion: 2012
Study completion: 2012
First posted: Mar 2, 2009
Registry last updated: May 30, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting