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NCT Number: NCT05715450

Falciformopexy for Treatment Perforated Peptic Ulcer.

Use the falciform ligament flap for the treatment of perforated peptic ulcer

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Key information

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Peptic ulcer perforation (PUP) is one in all the foremost common critical surgical emergencies. The omentum flap is usually wont to cover a PUP. However, the omentum can not be utilized in cases of severe peritonitis or previous surgical removal. this is often the primary study conducted in Vietnam that was designed to analyse the outcomes of patients with PUPs who were treated using the ligament.

In the population, the prevalence of ulcer disease supported physician diagnosis ranges from 0.12% to 1.50%, and hospitalization rates range from 0.10% to 0.19%. ulceration perforation (PUP) is one of the foremost common surgical emergencies worldwide, which is necessitate emergent surgical intervention.

the death rate of PUPs is between 1.3% and 20%, and mortality thanks to a perforation of a gastric ulcer is over mortality because of a perforation of a duodenal ulcer (40% vs 10%) . Some studies have shown that having comorbidities, being over 70 years old, undergoing surgical procedure after 36 h, PUP diameter greater than 1 cm2 and postoperative com- plications are associated with mortality. The technique of using the omental patch for repair PUP is commonest now thanks to mobility and vascularity but is also using the falciform ligament in some cases due to highly vascularity.

The technique of using the falciform ligament for the treatment of PUPs was reported in 1978 by Fry . The purpose of the study was to explain the technique and therefore the results of using the falciform ligament for the treat- ment of PUPs during a large volume surgical centre in Assuit university hospital found the falciform patch to be a successful technique in repair PUP and is assumed to be as effective as omental patch but more advantage because of highly vascular.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Any cases presented with PPU within age from 18 till 70 years.

Exclusion criteria

  • malignancy.
  • Previous GIT and liver surgery.
  • nonoperative treatment.

Treatment and study plan

Falciformopexy for Treatment Perforated Peptic Ulcer

Procedure

use the falciform ligament on perforated peptic ulcer

Primary outcomes

  1. Falciformopexy for Treatment Perforated Peptic Ulcer

    Time frame: Baseline

    The aim is to decrease incidence of leakage from the perforated peptic ulcer by using the falciform ligament for repair of the perforated peptic ulcer.

    Firstly, the investigator will seek to repair the perforation using suture to approximate edges then use falciform ligament as a secound layer to ensure security and prevent postoperative leakage that will lead to peritonitis and death.

Study contacts

Contact information is provided by the study sponsor or research team.

Doaa Hamada Abd elbaset

CONTACT

[email protected]

01028971942

Mostafa Ahmed Hamad

CONTACT

[email protected]

+201222438186

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Falciformopexy for Treatment Perforated Peptic

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
Feb 8, 2023
Registry last updated
Mar 10, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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