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OpenTrials
Completed

NCT Number: NCT05183061

Factors Associated With Post-induction Hypotension in iNPH Patient Undergoing VP and LP Shunt

This study is a retrospective work involving the review of patients who were scheduled for VP or LP shunt in Siriraj Hospital, Mahidol University, Thailand. The sample size calculation was based on the rule of thumbs of the logistic regression comprising 18 risk factors. The incidence of post-induction hypotension according to our institution's pilot study November 2019-January 2020) was 47%. With 10% addition for missing data and other possible reasons, the sample size was 426. The primary objective of the study is to report the factors associated with post-induction hypotension in iNPH patients undergoing VP or LP shunt procedures. Our secondary objective is to determine the incidence of post-induction hypotension in these patients.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Anesthesiology Department

Bangkok, 10700, Thailand

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Elective cases of iNPH scheduled for VP and LP shunt
  • Patients aged > 18 years old

Exclusion criteria

  • Emergency cases

Treatment and study plan

Ehedrine Norepineprine

Drug

No interventions required considering that this was a retrospective study.

Primary outcomes

  1. Factors associated with post-induction hypotension in iNPH patients undergoing VP or LP shunt procedures

    Time frame: 9 months

    Risk factors associated with post-induction hypotension after administration of anesthetic agents

Sponsors and collaborators

Lead sponsor

Mahidol University

Other

Registry information

Official study title

Factors Associated With Post-induction Hypotension in Idiopathic Normal Pressure Hydrocephalus (iNPH) Patient Undergoing Ventriculoperitoneal (VP) and Lumbar Peritoneal (LP) Shunt

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jan 10, 2022
Registry last updated
Jan 10, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.