Factors Associated With Breast Cancer Risks and Outcomes

The purpose of this study is to learn more about risks and outcomes of breast cancer in people with different backgrounds. Tissue and blood will be collected from participants for research purposes. Participants will complete questionnaires during their standard medical care. The study will not provide treatment for cancer or any other condition.

Recruiting

Interested in participating?

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Key information

Conditions

Breast Cancer Breast Diseases Breast Neoplasms Neoplasms Neoplasms by Site Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Memorial Sloan Kettering Cancer Center Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Women 18 years and older who are patients with a suspicious breast finding who present to breast radiology at MSK for biopsy or any new breast cancer patient seen at MSK undergoing surgery.

Inclusion criteria

A patient cannot be considered eligible for this study unless the following conditions are met.

Patients with a suspicious breast finding who present to breast radiology at MSK for biopsy or any new breast cancer patient who is a surgical candidate seen at MSK.
Women 18 years of age and older are eligible to participate in the study.

Exclusion criteria

Patients presenting with a suspicious breast mass or breast cancer less than 1 cm.
Patients presenting to clinic with only microinvasion
Patients who are less than 18 years of age
Patients unable to complete the survey, including IDMC patients.

Treatment and study plan

Survey

Other

Complete surveys:

Baseline (within 6 months of enrollment)
1st follow-up survey (approx. 6 months to 12 months)
2nd follow-up survey and/or blood collection (approx. 3 years +/- 6 months)
3rd follow-up survey and/or blood collection (approx. 5 years +/- 6 months)

Primary outcomes

Recurrence Free Survival/RFS

Time frame: 5 years

RFS as defined by the STEEP 2.0 guidelines

Study contacts

Contact information is provided by the study sponsor or research team.

George Plitas, MD

CONTACT

[email protected]

646-888-5368

Neha Goel, MD, MPH

CONTACT

[email protected]

646-888-4298

Sponsors and collaborators

Lead sponsor

Memorial Sloan Kettering Cancer Center

Other

Registry information

Official study title

Genomic and Non-Genomic Factors Associated With Breast Cancer Risk Factors and Outcomes

Important dates

Study start: 2025
Primary completion: 2031
Study completion: 2031
First posted: Dec 19, 2025
Registry last updated: Apr 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Recruiting