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NCT Number: NCT07747571

Factors Associated With Acceptance of Home-Based Pulmonary Telerehabilitation in COPD

Pulmonary rehabilitation improves symptoms, exercise capacity, and quality of life in people with chronic obstructive pulmonary disease (COPD), but access and participation may be limited by travel, organizational, logistical, and personal barriers. Home-based pulmonary telerehabilitation may reduce some of these barriers, although not all eligible individuals accept this mode of care. Identifying the characteristics associated with acceptance or refusal of this model is therefore essential to better define the population most likely to benefit from this approach, tailor the program's delivery and content, and identify potential remaining barriers in order to improve access to care.

This retrospective study will use existing data from adults with COPD who were screened at ADIR Association between May 2024 and April 2025 for an 8-week home-based pulmonary telerehabilitation feasibility study. Of 50 potentially eligible individuals, 21 accepted participation and 29 declined. Demographic, clinical, functional, psychological, and geographic characteristics will be compared between individuals who accepted and those who declined participation. Documented reasons for refusal will be described, and factors associated with refusal will be explored using logistic regression.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

ADIR Association

Rouen, Normandy, 76000, France

Location contact

Tristan Bonnevie, PhD

CONTACT

[email protected]

0235592970 ext. +33

Tristan Bonnevie, PhD

PRINCIPAL_INVESTIGATOR

About this study

ACCEPT-TELEREHAB is a single-center retrospective observational cohort study based on data collected during screening for the TELEREHAPP feasibility study (ClinicalTrials.gov identifier NCT05314686). The source cohort comprises all individuals with COPD who were screened and considered potentially eligible for an 8-week home-based pulmonary telerehabilitation program at ADIR Association between May 2024 and April 2025. Participants will be classified according to the decision recorded at screening: acceptance or refusal of the proposed telerehabilitation program.

Data will be extracted from the original screening file, medical records, and information available from the pulmonary rehabilitation referral and assessment. Variables of interest include age, sex, body mass index, COPD severity, comorbidities, available pulmonary function and exercise-test data, long-term oxygen therapy, dyspnea, quality of life, psychological status, functional exercise capacity, previous pulmonary rehabilitation, and the setting of any previous pulmonary rehabilitation program. When a reason for declining participation was documented, it will be coded retrospectively into descriptive categories; more than one category may be assigned to a single participant.

Home-to-center distance and estimated travel time will be derived using a standardized mapping procedure. The residential address available at screening will be used to calculate the fastest car journey to ADIR Association for a standardized arrival time of 9:00 AM on a working Tuesday outside public holidays and school vacations.

Continuous variables will be summarized using means and standard deviations or medians and interquartile ranges, as appropriate. The acceptance and refusal groups will be compared using independent-samples t tests or Wilcoxon-Mann-Whitney tests for continuous variables and chi-square or Fisher exact tests for categorical variables. Differences will be reported with 95 percent confidence intervals. Refusal to participate will be the dependent variable in univariable and multivariable logistic regression models. Results will be reported as odds ratios with 95% confidence intervals.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults with COPD who were screened at ADIR Association between May 2024 and April 2025 for an 8-week home-based pulmonary telerehabilitation feasibility study. Please, refer to ClinicalTrials.gov identifier NCT05314686.

Exclusion criteria

  • Not applicable

Treatment and study plan

No intervention

Other

None for the present retrospective study.

Primary outcomes

  1. Participation Decision Regarding Home-Based Pulmonary Telerehabilitation

    Time frame: At screening, before initiation of the proposed 8-week telerehabilitation program

    The participation decision recorded at screening will be classified as acceptance or refusal of the proposed 8-week home-based pulmonary telerehabilitation program. The number and percentage of participants in each category will be reported.

Secondary outcomes

  1. Documented Reasons for Refusal of Home-Based Pulmonary Telerehabilitation

    Time frame: At screening, when the participation decision was documented

    Reasons for refusal documented in the screening file or medical record will be coded retrospectively into descriptive categories and reported as numbers and percentages among participants with an available reason. More than one category may be assigned to a participant.

  2. Distance From the Participant Residence to the Pulmonary Rehabilitation Center

    Time frame: At the time of screening

    Distance from the residence recorded at screening to ADIR Association will be calculated using a standardized mapping procedure and expressed in kilometers. The derived value will be compared between participants who accepted and declined telerehabilitation.

  3. Estimated Travel Time From the Participant Residence to the Pulmonary Rehabilitation Center

    Time frame: At the time of screening

    The estimated duration of the fastest car journey from the residence recorded at screening to ADIR Association will be calculated using a standardized mapping procedure and expressed in minutes. The derived value will be compared between participation-decision groups.

  4. Age at screening

    Time frame: At the time of screening

    Age in years at screening will be compared between participants who accepted and declined telerehabilitation.

  5. Sex distribution

    Time frame: At the time of screening

    The number and percentage of female and male participants will be reported for each participation-decision group.

  6. Body mass index at screening

    Time frame: At the time of screening

    Body mass index will be calculated as weight in kilograms divided by height in meters squared and compared between groups.

  7. Chronic Obstructive Pulmonary Disease Severity

    Time frame: At the time of screening

    COPD severity available in the medical record, including Global Initiative for Chronic Obstructive Lung Disease (GOLD) spirometric grade when documented, will be reported by participation-decision group.

  8. Long-term oxygen status

    Time frame: At the time of screening

    The number and percentage of participants receiving long-term oxygen therapy will be reported for each group.

  9. Modified Medical Research Council Dyspnea Scale Score

    Time frame: At the time of screening

    Functional dyspnea will be assessed using the modified Medical Research Council (mMRC) dyspnea scale. Scores range from 0 to 4, with higher scores indicating greater dyspnea-related disability.

  10. Visual Simplified Respiratory Questionnaire Score

    Time frame: At the time of screening

    Respiratory quality of life will be assessed using the Visual Simplified Respiratory Questionnaire (VSRQ). Scores range from 0 to 80, with higher scores indicating better respiratory quality of life.

  11. Saint George's Respiratory Questionnaire

    Time frame: At the time of screening

    Respiratory quality of life will be assessed using the Saint George's Respiratory Questionnaire (SGRQ). Scores range from 0 to 100, with lower scores indicating better respiratory quality of life.

  12. Hospital Anxiety and Depression Scale Anxiety Subscale Score

    Time frame: At the time of screening

    Anxiety symptoms will be assessed using the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A). Scores range from 0 to 21, with higher scores indicating more severe anxiety symptoms.

  13. Hospital Anxiety and Depression Scale Depression Subscale Score

    Time frame: At the time of screeining

    Depressive symptoms will be assessed using the depression subscale of the Hospital Anxiety and Depression Scale (HADS-D). Scores range from 0 to 21, with higher scores indicating more severe depressive symptoms.

  14. Six-minute walk distance

    Time frame: At the time of screening

    Functional exercise capacity will be expressed as the distance walked during the 6-minute walk test, in meters.

  15. Six-Minute Stepper Test Performance

    Time frame: At the time of screening

    Functional exercise capacity will be expressed as the number of steps completed during the 6-minute stepper test.

  16. One-Minute Sit-to-Stand Test Performance

    Time frame: At the time of screening

    Functional exercise capacity will be expressed as the number of complete repetitions performed during the 1-minute sit-to-stand test.

  17. Peak Oxygen Uptake During Cardiopulmonary Exercise Testing

    Time frame: At the time of screening

    Peak oxygen uptake (VO2peak), when available, will be extracted from the most recent cardiopulmonary exercise test and compared between groups.

  18. Previous Participation in Pulmonary Rehabilitation

    Time frame: At the time of screening

    The number and percentage of participants with a previous pulmonary rehabilitation program will be reported for each group.

  19. Setting of Previous Pulmonary Rehabilitation

    Time frame: At the time of screening

    When available, the setting of previous pulmonary rehabilitation will be classified as center-based, home-based, telerehabilitation, private physiotherapy practice, hybrid or mixed, other, or unknown.

  20. Pulmonary Function at Screening - Forced Expiratory Volume in 1 Second

    Time frame: At the time of screening

    The most recent forced expiratory volume in 1 second (FEV1) available at the time of screening for the initial telerehabilitation study will be extracted from the medical record. FEV1 will be reported as an absolute volume in liters and as a percentage of the predicted value. Values will be compared between participants who accepted and those who declined participation in the home-based pulmonary telerehabilitation program.

  21. Pulmonary Function at Screening - Forced Vital Capacity

    Time frame: At the time of screening

    The most recent forced vital capacity (FVC) available at the time of screening for the initial telerehabilitation study will be extracted from the medical record. FVC will be reported as an absolute volume in liters and as a percentage of the predicted value. Values will be compared between participants who accepted and those who declined participation in the home-based pulmonary telerehabilitation program.

  22. Pulmonary Function at Screening - FEV1/FVC Ratio

    Time frame: At the time of screening

    The most recent ratio of forced expiratory volume in 1 second to forced vital capacity (FEV1/FVC) available at the time of screening for the initial telerehabilitation study will be extracted from the medical record. The FEV1/FVC ratio will be reported as a percentage. Values will be compared between participants who accepted and those who declined participation in the home-based pulmonary telerehabilitation program.

  23. Pulmonary Function at Screening - Residual Volume

    Time frame: At the time of screening

    The most recent residual volume (RV) available at the time of screening for the initial telerehabilitation study will be extracted from the medical record. RV will be reported as an absolute volume in liters and as a percentage of the predicted value. Values will be compared between participants who accepted and those who declined participation in the home-based pulmonary telerehabilitation program.

  24. Pulmonary Function at Screening - Total Lung Capacity

    Time frame: At the time of screening

    The most recent total lung capacity (TLC) available at the time of screening for the initial telerehabilitation study will be extracted from the medical record. TLC will be reported as an absolute volume in liters and as a percentage of the predicted value. Values will be compared between participants who accepted and those who declined participation in the home-based pulmonary telerehabilitation program.

  25. Pulmonary Function at Screening - Vital Capacity

    Time frame: At the time of screening

    The most recent slow vital capacity (VC) available at the time of screening for the initial telerehabilitation study will be extracted from the medical record. VC will be reported as an absolute volume in liters and as a percentage of the predicted value. Values will be compared between participants who accepted and those who declined participation in the home-based pulmonary telerehabilitation program.

Study contacts

Contact information is provided by the study sponsor or research team.

Tristan Bonnevie, PhD

CONTACT

[email protected]

0235592970 ext. +33

Sponsors and collaborators

Lead sponsor

ADIR Association

Other

Collaborators

  • Hopital La Musse
  • University of Rouen Normandie

Registry information

Official study title

Factors Associated With Acceptance or Refusal of Participation in a Home-Based Pulmonary Telerehabilitation Program Among Adults With Chronic Obstructive Pulmonary Disease: A Retrospective Study

Acronym: ACCEPT-TELE-R

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Aug 5, 2026
Registry last updated
Aug 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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