Skip to main content
OpenTrials
Completed

NCT Number: NCT06396351

Factors Affecting Abdominal Compliance During CO2 Insufflation in Laparoscopic Abdominal Surgery

The authors aimed to evaluate factors influencing abdominal compliance in laparoscopic abdominal surgery.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Laparoscopic Surgery

Age range

18 year–82 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Ankara University Medical School Anesthesiology and ICU Department

Ankara, Turkey (Türkiye)

About this study

During laparoscopic surgery, pneumoperitoneum is achieved by insufflating carbon dioxide (CO2) gas into the abdominal cavity to create a safe working space. Pneumoperitoneum-induced elevation in intra-abdominal pressure (IAP) can result in various complications. Abdominal compliance (AC), represents the slope of the P-V curve of the abdominal cavity and is a measure of the ease of abdominal dilatation, is important to balance between surgical safety and complications. The aim of this study was to determine the effect of demographic and anatomic variables on AC.

The study included 90 patients who underwent laparoscopic abdominal surgery. Subcutaneous adipose tissue and abdominal muscle thickness were measured ultrasonographically. Mean AC was calculated during insufflation using the formula (ΔV/ΔP). The relationship between demographic and anatomic variables and AC was investigated

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Aged between 18 and 82 years ASA class I-III Elective abdominal surgery with laparoscopic technique

-

Exclusion criteria

Aged below 18 and above 82 ASA IV-V

Treatment and study plan

Laparoscopic surgery

Procedure

effect of carbondioxide insufflation on abdominal compliance was evaluated

Other names: Carbondioxide insufflation

Primary outcomes

  1. The factors affecting abdominal compliance

    Time frame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery

    Effect of rectus muscle thickness and lateral abdominal muscle group thickness on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

Secondary outcomes

  1. The factors affecting abdominal compliance

    Time frame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery

  2. The factors affecting abdominal compliance

    Time frame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery

    Effect of age on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

  3. The factors affecting abdominal compliance

    Time frame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery

    Effect of gender on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

  4. The factors affecting abdominal compliance

    Time frame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery

    Effect of ASA physical status on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

  5. The factors affecting abdominal compliance

    Time frame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery

    Effect of body mass index on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

  6. The factors affecting abdominal compliance

    Time frame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery

    Effect of previous surgery on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

  7. The factors affecting abdominal compliance

    Time frame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery

    Effect of pregnancy on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

  8. The factors affecting abdominal compliance

    Time frame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery

    Effect of subcutaneous adipose tissue thickness on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

Sponsors and collaborators

Lead sponsor

Ankara University

Other

Registry information

Official study title

Factors Influencing Abdominal Compliance During CO2 Insufflation in Patients Undergoing Laparoscopic Abdominal Surgery

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
May 2, 2024
Registry last updated
May 2, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.