Skip to main content
OpenTrials
Completed

NCT Number: NCT05890079

External Oblique Intercostal Plane Block for Liver Transplantation Donors

Postoperative pain management is one of the important factors to improve rehabilitation and enhance recovery. External oblique intercostal plane block may be used for abdominal wall analgesia to provide effective analgesia for abdominal surgery. The aim of this study is to investigate the postoperative analgesic efficacy of external oblique intercostal plane block and subcostal transversus abdominis plane block in living liver donors.

Researchers will compare the external oblique intercostal plane block group with subcostal transversus abdominis plane block to see if the external oblique intercostal plane block is effective for postoperative analgesia in living liver donors.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Liver Transplantation Donor Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Postoperative Pain Signs and Symptoms

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Istinye University Hospital

Istanbul, Turkey (Türkiye)

About this study

Patients scheduled for living donor hepatectomy will be separated into 2 groups: Subcostal Transversus Abdominis Plane Block Group and External Oblique Intercostal Plane Block Group. Patients in Subcostal Transversus Abdominis Plane Block will be performed subcostal transversus plane block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Patients in External Oblique Intercostal Plane Block Group will be performed bilateral External Oblique Intercostal Plane Block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Morphine consumption for first postoperative 24 hours, visual analog scale scores, time to need for first rescue analgesia, amount of rescue analgesic drug, incidence of postoperative nausea and vomiting will be recorded.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 18 and 75 years
  • Patients with American Society of Anesthesiology (ASA) physical status I-II
  • Patients scheduled for a living donor hepatectomy

Exclusion criteria

  • Allergy to local anesthetics
  • Coagulopathy
  • Skin infection at the block area
  • Advanced renal failure
  • Chronic pain syndromes
  • Alcohol or drug abuse
  • Psychiatric disorders

Treatment and study plan

Subcostal Transversus Abdominis Plane Block

Other

External oblique intercostal plane block will be administered at the end of the surgery and after skin closure.

External Oblique Intercostal Plane Block

Other

External oblique intercostal plane block will be administered at the end of the surgery and after skin closure. .

Primary outcomes

  1. Morphine consumption

    Time frame: Postoperative 24 hours

    The amount of morphine required by the patient and given by the device will be recorded for the first 24 hours.

Secondary outcomes

  1. Postoperative visual analog scale scores

    Time frame: Postoperative 24 hours

    Postoperative pain will be assessed using a visual analog scale (VAS) (from 0 = no pain to 10 = maximum possible pain) for the first 24 hours.

  2. Rescue analgesic drug consumption

    Time frame: postoperative 24 hours

    The amount of rescue analgesic in mg required by the patient will be recorded for the first 24 hours.

  3. Incidence of postoperative nausea and vomiting

    Time frame: postoperative 24 hours

    Number of patients developing postoperative nausea and vomiting will be recorded for the first 24 hours

Sponsors and collaborators

Lead sponsor

Istinye University

Other

Registry information

Official study title

External Oblique Intercostal Plane Block for Postoperative Analgesia in Living Liver Donors

Important dates

Study start
2023
Primary completion
2023
Study completion
2024
First posted
Jun 6, 2023
Registry last updated
Mar 19, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.