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Completed

NCT Number: NCT07445776

Extended Platelet Rich Fibrin Versus Allograft as Space Filling Material

Twenty-eight patients seeking prosthetic replacement of non-restorable single rooted maxillary teeth by dental implant will be selected from the outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University

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Key information

Conditions

Immediate Implant Placement Gap Filling With Allograft Gap Filling With e-PRF

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Dentistry, Mansoura University

Al Mansurah, 002, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with badly destructed teeth due to trauma or caries.
  • Patients willing to complete the study follow up intervals.
  • Patients with good oral hygiene.
  • Adequate inter-arch space that can accommodate implant abutment and future restoration.
  • No gender preference in selection of the patients.

Exclusion criteria

  • Patients with systemic diseases that absolutely contraindicate dental implant placement.
  • Patients with parafunctional habits (bruxism and clenching).
  • Heavy smokers (i.e. More than 20 cigarettes/day)34 and alcoholism.
  • Presence of local infection or lesions at the proposed area for dental implant.
  • Pregnancy.
  • Patient taking drugs that could affect bone healing process as immunosuppressive drugs and bisphosphonates.
  • Patients with bad oral hygiene and untreated periodontal disease
  • Uncooperative patients

Treatment and study plan

Allograft

Other

after immediate implant placement the gap will be filled with allograft

e-PRF

Other

after immediate implant placement the gap will be filled with e-PRF

Primary outcomes

  1. Implant stability

    Time frame: immediately ,6months follow up & one year

    Resonance frequency analysis (RFA) values expressed as implant stability quotient (ISQ) will be recorded by (Osstell Mentor Device)

Secondary outcomes

  1. Marginal bone loss

    Time frame: immeditely,6months follow up & one year

    CBCT was done to assess the buccal marginal bone loss

Sponsors and collaborators

Lead sponsor

Mansoura University

Other

Registry information

Official study title

Extended Platelet Rich Fibrin Versus Allograft as Space Filling Material in Immediate Dental Implant Placement

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Mar 3, 2026
Registry last updated
Mar 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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