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NCT Number: NCT06553911

Exploring the Application Efficacy of Artificial Intelligence (AI) Diagnostic Tools in Medical Imaging (MI) of Respiratory(R) Infectious (I) Disease (D)

The early identification and severe warning of acute respiratory infectious diseases are of paramount importance. Utilizing effective means to make correct diagnoses of the source of infection at an early stage is the premise of all effective measures. AI-MID is a research initiative that uses artificial intelligence tools to assist in the clinical medical imaging diagnosis of respiratory diseases, aiming to reduce the time doctors spend reviewing images, increase work efficiency, and enhance the sensitivity and specificity of pneumonia detection, thereby improving the detection rate of pneumonia at the grassroots level. This approach facilitates precise prevention, accurate diagnosis, and precise treatment.

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Key information

Age range

1 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Huashan Hospital

Shanghai, 200040, China

Location status: Recruiting

Location contact

Wenhong Zhang, Professor

CONTACT

[email protected]

(86)52889999

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1-90 years old, gender not specified.
  • Exhibits symptoms of respiratory tract infection
  • Must have etiological examination results
  • Must have imaging data;

Exclusion criteria

  • Severe artifacts in medical images
  • Clinical diagnosis indicates concurrent pulmonary edema
  • Dual review results in unclear diagnosis or potential misdiagnosis
  • Other situations that may cause difficulties in reading the films, or as determined by the researcher, the study participant is deemed unsuitable for enrollment.

Treatment and study plan

Artificial Intelligence-based medical imaging interpretation

Other

In the AI interpretation group, using clinical information, imaging data, and corresponding etiological results of the study participants, an AI diagnostic tool is established to specifically recognize patients' chest medical imaging and construct corresponding diagnostic conclusions.

Primary outcomes

  1. Evaluating the Diagnostic Efficacy of Artificial Intelligence Diagnostic Tools in Medical Imaging of Respiratory Infectious Diseases

    Time frame: 2 years

    To evaluate the diagnostic efficacy of computer-aided detection (CAD) software in the identification of pulmonary infections, the study will employ the following methods:

    Imaging Criteria: Experienced radiologists will interpret the medical imaging of study participants, serving as the imaging standard.

    Computer-Aided Detection: Concurrently, the CAD software will analyze the participants' medical imaging to generate diagnostic results.

    Efficacy Assessment: The accuracy and consistency of the CAD software will be evaluated by comparing its interpretations with the diagnoses made by the radiologists.

Secondary outcomes

  1. Utilizing artificial intelligence tools for early identification and severe warning of respiratory infectious diseases

    Time frame: 2 years

    By integrating the medical imaging of study participants with the corresponding respiratory pathogen detection results, these data will be used as the training set input into the AI diagnostic tool, enabling it to undergo deep learning. This process will establish an AI diagnostic tool based on pathogen imaging. After completing the data collection for both retrospective and prospective study sections, we plan to evaluate the disease progression and prognosis of the study participants based on survival analysis and predictive modeling. By integrating clinical data and imaging data, we aim to enhance the accuracy and precision of the prognostic assessment model. The model will be continuously optimized according to the changes in the conditions of study participants enrolled over different time periods.

Study contacts

Contact information is provided by the study sponsor or research team.

Wenhong Zhang

CONTACT

[email protected]

(86)52889999

Sponsors and collaborators

Lead sponsor

Huashan Hospital

Other

Registry information

Acronym: AI-MIRID

Important dates

Study start
2022
Primary completion
2025
Study completion
2026
First posted
Aug 14, 2024
Registry last updated
Aug 14, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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