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NCT Number: NCT05440123

Experimentation With Screening for Bronchopulmonary Cancer and Primary Cardiovascular Prevention, Early Management of COPD and an Offer Exempted From Smoking Cessation

The study consists of recruiting a target population by sending a letter from the Regional Center for Cancer Screening in Ile de France.

In the screening program, a battery of examinations will be carried out at inclusion, one year, 2 years, 3 years, 4 years and 5 years.

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Key information

Age range

55 year–74 year

Sex eligibility

All sexes

Study type

Observational

About this study

The patients will be recruited by correspondence by by sending a letter from the Regional Center for Cancer Screening in Ile de France.

When the patient has agreed to participate, a screening program will be carried out The screening program includes performing a low-dose chest CT scan (STBD), spirometry, blood sampling (biobank + screening for cardiovascular risk factors) on inclusion, at 1 year and at 2 years. Subsequently, a telephone interview will be scheduled for 3 years to collect medical information, for a total follow-up period of 5 years. At each visit, a structured offer of smoking cessation will be proposed and a collection of the quality of life will be carried out. Each year, a telephone call from participants will be scheduled in order to maximize participation

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women and men
  • Age: 55 to 74 years old
  • Smokers at more than 20 pack-years weaned for less than 15 years
  • Affiliated to a social security organization

Exclusion criteria

  • Presence of signs of PBC
  • Subjects with a personal history of PBC of less than 5 years or under treatment
  • Presence of serious comorbidities involving the vital prognosis at 6 months
  • Subjects who have already benefited from a chest CT scan less than one year old.
  • Refusal to participate in the study
  • Absence of exposure to tobacco or insufficient exposure to tobacco or withdrawal > 15 years
  • Patient on long-term oxygen therapy
  • Metal implants (thorax, spine) which can cause a deterioration in the quality of the image of the low dose scanner
  • Subject included in another study protocol

Treatment and study plan

screening for bronchopulmonary cancer

Other

The screening program includes performing a low-dose chest CT scan (STBD), spirometry, blood sampling (biobank + screening for cardiovascular risk factors) on inclusion, at 1 year and at 2 years. Subsequently, a telephone interview will be scheduled for 3 years to collect medical information, for a total follow-up period of 5 years. At each visit, a structured offer of smoking cessation will be proposed and a collection of the quality of life will be carried out. Each year, a telephone call from participants will be scheduled in order to maximize participation

Primary outcomes

  1. Rate of population participation in PBC screening

    Time frame: Baseline

Study contacts

Contact information is provided by the study sponsor or research team.

Camille JUNG

CONTACT

[email protected]

0145175000

Sébastien Gendarme, MD

CONTACT

[email protected]

01.57.02.20.90

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Intercommunal Creteil

Other

Registry information

Official study title

Bronchopulmonary Cancer Screening Program and Primary Cardiovascular Prevention, Early Management of COPD and Smoking Cessation

Acronym: LUMASCAN-2

Important dates

Study start
2025
Primary completion
2027
Study completion
2032
First posted
Jun 30, 2022
Registry last updated
Jun 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.