Pregnancy of unknown location (PUL) is a clinical scenario in which a patient has cramping or vaginal bleeding and is known to be pregnant based on physical and laboratory evaluations, but an intrauterine or extrauterine pregnancy cannot be visualized on ultrasound examination. At present, follow-up for these patients includes multiple blood draws and repeat ultrasounds to confirm if the pregnancy is inside the uterus or in a riskier location outside the uterus (ectopic pregnancy); however, most of these patients will be low-risk for ectopic pregnancy and do not need intensive follow-up. This study aims to improve the risk-stratification of PUL patients after a single encounter to allow for patients at low-risk for ectopic pregnancy to be discharged from intensive follow-up.
Recruitment: Up to 120 participants will be recruited for this study
Entry Criteria:
- PUL diagnosis in the UC Davis Emergency Department or Obstetrics and Gynecology Office
- Vaginal bleeding
- Clinically stable
- English-speaking
Consent - Eligible Patients will be invited to participate by a member of the clinical care team. Written consent will be required.
Confidentiality - The Principal Investigator will preserve the confidentiality of participants taking part in the study. All patient information will be stored on a secure computer with password protection. All information will be de-identified.
Conflict of interest - none