University Hospital Zurich
Zurich, Canton of Zurich, 8091, Switzerland
Location status: Recruiting
Location contact
Malcolm Kohler, MD
CONTACT
Noriane Sievi, MSc
CONTACT
Recruiting
NCT Number: NCT05456009
Exhaled Breath Analysis in Human Subjects
Identification of exhaled breath pattern of human subjects
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
Breath analysis with mass spectormetry as a non-invasive method to identfy exhaled breath patterns.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- >= 18 years
- Informed consent
Exclusion criteria
- specific exclusion criteria for different subgroups
Treatment and study plan
No intervention
OtherNo intervention
Primary outcomes
-
Exhaled breath pattern
Time frame: baseline
mass spectrometric profile of exhaled breath pattern of human subjects
Secondary outcomes
-
Chemical structure of exhaled breath molecules
Time frame: baseline
The identification of the chemical structure of exhaled breath molecules
-
Body fluids
Time frame: baseline
The correlations of identified molecules in exhaled breath with body fluids
-
Disease marker
Time frame: baseline
The correlation of a distinct disease marker with a breath print or breath feature
-
Distinguish between disease
Time frame: baseline
The use of a breath print to distinguish between disease and/or health state
-
Health state
Time frame: baseline
The correlation of breath prints to subjective health state and/or quality of life
-
Medication
Time frame: baseline
Response to medication and toxicity as a function of blood/breath drug concentrations
-
Excretion of drugs
Time frame: baseline
Correlation between lung function and the excretion of drugs in exhaled breath
Study contacts
Contact information is provided by the study sponsor or research team.
Malcolm Kohler, MD
CONTACT
Noriane Sievi, MSc
CONTACT
Sponsors and collaborators
Lead sponsor
University of Zurich
Other
Collaborators
- Deep Breath Intelligence (DBI)
Registry information
Official study title
Exhaled Breath Analysis by Secondary Electrospray Ionization - Mass Spectrometry (SESI-MS) in Human Subjects
Important dates
- Study start
- 2019
- Primary completion
- 2030
- Study completion
- 2030
- First posted
- Jul 13, 2022
- Registry last updated
- May 29, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.