Exercise Training Study of Patients With Claudicatio Intermittens

Patients with intermittent claudication will by a web-based program be randomized to either "five plus training" or walking at least 30 minutes three times per week. During the "five plus training" the participants are standing in front of a wall, which is used for support of the balance. The body is lifted with the calf musculature to the maximal height that the subject can achieve. This is repeated until pain is felt in the calf musculature. Following the initiation of pain the subject performs five extra repetitions. The five extra calf raises are included to secure induction of ischemia followed by reperfusion to secure maximal training effect.

The patients are followed by absolute walking distance on a treadmill, quality of life questionnaire, and Ankle-brachial index.

Inclusion criteria

• Pain in the calves after 300 m, or less measured on a treadmill
• Stable symptoms last 6 months or more
• The pain must be gone within 5 minutes after the patients stop walking
• Ankle-Brachial index at 0.7 or lower at rest
• Using statins and antiplatelet drugs since at least 3 months
• age> 18 years
• Signed consent

Exclusion criteria

• pain in the hips or elsewhere outside the calves while walking
• Remaining pain more than 5 minutes after stopped walking.
• Impossible to compress the arteries while measruing ABI or ABI lower than 0.4
• Use of statins and antiplatelet drugs less than 3 months
• symptoms less than 6 months
• Diabetes measured with HbA1c being over 48 mmol/mol (6%)
• Revascularisation the last 6 months
• Pain in the calves after longer than 300 m measured on a treadmill
• Reduced mobility in the ankles
• Reduced physical ability to perform a test on a treadmill.
• Age less than 18 years
• General conditions that impairs the ability to take part in a training study including Obesity, KOLS, heart disease, arthrosis, inflammatory joint diseases .
• No Signed consent