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Completed

NCT Number: NCT07195630

Exercise-Induced Changes in Serum Oncostatin M Levels in Recreationally Active Males

The aim of this study was to compare the effects of workload-matched acute moderate-intensity continuous exercise (MICE) and high-intensity interval exercise (HIIE) on serum OSM levels on a cycle ergometer in recreationally active, healthy men. Fifteen participants participated in both MICE and HIIE sessions. The HIIE session consisted of 10 x 1 min intervals at 90% of maximal oxygen uptake (VO2max) separated by a 75-second active recovery period at 60 W, whereas the MICE session consisted of a ~21 min exercise session at 55% of VO2max. Blood samples were collected before (Pre) and immediately after (Post) acute MICE and HIIE sessions. Serum OSM levels were measured by the ELISA method.

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Key information

Conditions

The Aim of This Study is to Evaluate the Effects of Acute Exercise on Serum Oncostatin M Levels in Healthy, Recreationally Active Males

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Hacettepe University

Ankara, Çankaya, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Engaged in regular exercise/training in the last 6 months,
  • 18-30 years of age,
  • Body mass index (BMI) in the range of 18.5-24.9 kg/m².

Exclusion criteria

  • Having a chronic disease that limits exercise,
  • Smoking,
  • Using any medication or supplement that may affect metabolism.

Treatment and study plan

Moderate-Intensity Continuous Exercise

Other

15 recreationally active males completed the ~21 min of exercise at 55% of VO2max, consisting of a 3-minute warm-up and 3-minute cool-down at 60 W.

High-Intensity Interval Exercise

Other

15 recreationally active males performed 10 x 1-minute intervals at 90% of VO2max, separated by 75 s of active recovery at 60 W, and a final 3-minute cool-down period at 60 W.

Primary outcomes

  1. Change from Pre- to Post-Exercise Levels of Oncostatin M

    Time frame: From baseline assessment of blood samples at pre-exercise to the assessment of blood sample analysis at the end of the post-exercise.

    Serum samples were collected at pre- and post-exercise time points, and serum oncostatin M levels were measured using a commercial ELISA kit

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Official study title

Both Acute Moderate-Intensity Continuous Exercise and High-Intensity Interval Exercise Increase Serum Oncostatin M Levels in Recreationally Active Males

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Sep 26, 2025
Registry last updated
Sep 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.