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Completed

NCT Number: NCT04706650

Exercise Capacity, Cardiovascular Risk Factors and Disease-related Variables in Axial Spondyloarthritis

The investigators aimed to study the associations between exercise capacity and cardiovascular (CV) risk factors in axial spondyloarthritis (axSpA) patients and to determine possible relationships with disease-related variables. Thirty eight patients and 38 controls were recruited in our cross-sectional controlled study. Comprehensive systemic and musculoskeletal examinations were carried out in both of the groups. Cardiovascular risk profile data, ASDAS-CRP, 10-year CV event risk, physical activity levels (IPAQ) were recorded. A maximal treadmill exercise test by Bruce protocol was administered to all participants.

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Key information

Conditions

Exercise Capacity Ankylosis Arthritis Axial Spondyloarthritis Bone Diseases Joint Diseases Musculoskeletal Diseases Spinal Diseases Spondylarthritis Spondylarthropathies Spondylitis

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • clinical diagnosis of axial SpA
  • must be able to walk

Exclusion criteria

  • established cardiac disease including structural heart diseases,
  • uncontrolled hypertension,
  • cardiac rhythm disorder,
  • unstable angina pectoris,
  • chronical renal and/or hepatic disease,
  • malignancy,
  • neuromuscular disease
  • musculoskeletal deformity
  • the history of an inflammatory arthritis for control group

Treatment and study plan

Primary outcomes

  1. Mean difference in exercise capacity of axSpA patients and controls

    Time frame: may- october 2014

    maximal METs achieved by a maximal treadmill test by Bruce protocol

Secondary outcomes

  1. Mean difference in heart rate recovery of axSpA patients and controls

    Time frame: may- october 2014

    peak heart rate achieved by maximal exercise minus heart rate at 1st minute of recovery phase

Sponsors and collaborators

Lead sponsor

Muğla Sıtkı Koçman University

Other

Registry information

Official study title

Exercise Capacity in Axial Spondyloarthritis and Factors Affecting it: a Cross-sectional Controlled Study

Important dates

Study start
2014
Primary completion
2014
Study completion
2014
First posted
Jan 13, 2021
Registry last updated
Jan 13, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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