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Completed

NCT Number: NCT01242735

Exercise and Health Intervention for Patients With Obsessive Compulsive Disorder (OCD)

The purpose of this study is to test the effect of a moderate-intensity aerobic exercise intervention for Obsessive Compulsive Disorder (OCD) patients interested in reducing symptoms. The investigators expect that this project will contribute much needed knowledge about the role that aerobic exercise can play in managing the effects of OCD. If moderate-intensity aerobic exercise is efficacious in helping individuals with OCD manage obsessions and compulsions, this will establish that aerobic exercise may be a valuable adjunct to other OCD treatments such as medication and therapy.

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Key information

Conditions

Obsessive Compulsive Disorder Anxiety Disorders Behavior Mental Disorders Motor Activity Obsessive-Compulsive Disorder

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Butler Hospital

Providence, Rhode Island, 02906, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • are between 18 and 65 years of age
  • are sedentary, i.e. have not participated in regular aerobic physical exercise for at least 90 minutes per week during the past three months
  • currently engaged in at least 12 weeks of stable dose pharmacotherapy and/or are currently engaged in cognitive-behavioral therapy for the past 13 weeks
  • meet Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) criteria for OCD as assessed by the Structured Clinical Interview for DSM Disorders, Patient Version (SCID-P)
  • have Y-BOCS score greater than 16

Exclusion criteria

  • DSM-IV diagnosis of substance abuse/dependence except for nicotine dependence
  • DSM-IV diagnosis of anorexia or bulimia nervosa
  • DSM-IV diagnosis of bipolar disorder
  • history of psychotic disorder or current psychotic symptoms
  • current suicidality or homicidality
  • marked organic impairment
  • physical or medical problems that would not allow for safe exercise participation
  • current pregnancy or intent to become pregnant during the next 12 weeks

Treatment and study plan

Aerobic Exercise

Behavioral

12-week moderate-intensity behavioral exercise intervention. Weekly sessions with an exercise physiologist who will also assign weekly exercise goals.

Health and Wellness

Behavioral

12-week health and wellness education control. Weekly sessions about 12 different topics related to OCD, led by an OCD expert.

Primary outcomes

  1. Yale-Brown Obsessive Compulsive Scale (Y-BOCS; OCD symptomatology)

    Time frame: 15 months

Sponsors and collaborators

Lead sponsor

Butler Hospital

Other

Collaborators

  • National Institute of Mental Health (NIMH)

Registry information

Official study title

Testing the Efficacy of an Exercise Intervention for Patients With OCD

Important dates

Study start
2010
Primary completion
2015
Study completion
2015
First posted
Nov 17, 2010
Registry last updated
Jul 22, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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