Executive Training and Anomia Therapy in Chronic Post-stroke Aphasia

Aphasia is a devastating acquired language impairment mainly caused by stroke, in which anomia is a quintessential clinical feature. If speech-language therapy (SLT) has been shown to be effective for persons with aphasia, the relative efficiency of one SLT strategy over another remains a matter of debate. The influential relationship between language, executive functions and aphasia rehabilitation outcomes has been addressed in a number of studies, but only few of them have studied the effect of adding an executive training to linguistic therapies.The aim of this study is to measure the efficiency of a protocol combining anomia therapy and executive training on naming skills and discourse in post-stroke aphasic persons at the chronic stage

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Key information

Conditions

Anomia Aphasia Communication Disorders Language Disorders Mental Disorders Nervous System Diseases Neurobehavioral Manifestations Neurodevelopmental Disorders Neurologic Manifestations Pathological Conditions, Signs and Symptoms Post-stroke Aphasia Signs and Symptoms Speech Disorders

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Uhmontpellier

Montpellier, 34295, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

18 < age > 80 years
adult person with chronic post-stroke aphasia (> 6 months postonset)
receiving SLT rehabilitation 3 times a Week

Exclusion criteria

presence of apraxia of speech
major impairment of comprehension
history of other neurological or psychiatric disease

Exclusion criteria

presence of apraxia of speech
presence of major impairment of comprehension
presence of history of other neurological or psychiatric disease

Treatment and study plan

Primary outcomes

Evolution of individual naming scores

Time frame: 2 days

Evolution of individual naming scores during baseline and treatment phases Participants are asked to name pictures from a personal naming task constituted of 100 black and white pictures and scores are expressed as percent of correct responses (min 0, max 100): higher percents meaning a better outcome. A visual analysis of the evolution of these scores along the course of the treatment will be conducted.
Comparison of discourse

Time frame: 2 days

Comparison of discourse scores before and after the treatment For each participant, four different samples of discourse are elicited before and after the treatment (picture description, personal narrative, book supported narrative, procedural information). The mean number of correct words per minute is then computed for each participant, and compared between the two time points, higher scores meaning a better outcome.

Secondary outcomes

Comparison of executive scores

Time frame: 2 days

Comparison of executive scores before and after the treatment Executive scores are computed before and after treatment for each participant, from the Modified Card Sorting Test (Nelson, 1976), in which higher number of categories achieved means a better outcome, and from a verbal fluency task in which higher number of words produced in 2 minutes means a better outcome

Sponsors and collaborators

Lead sponsor

University Hospital, Montpellier

Other

Registry information

Official study title

Combining Executive Training and Anomia Therapy in Chronic Post-stroke Aphasia : a Single Case Experimental Design -SCED Preliminary Study

Acronym: ETAT PSA

Important dates

Study start: 2021
Primary completion: 2021
Study completion: 2021
First posted: Nov 1, 2021
Registry last updated: Apr 12, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed