University of Illinois-Chicago
Chicago, Illinois, 60612, United States
Location status: Recruiting
NCT Number: NCT06241300
Deficits in executive functioning (EF) disproportionately impact children living in poverty and increase risk for psychopathology, particularly disruptive behavior disorders. This randomized clinical trial seeks to determine whether childhood EF, assessed across neural and behavioral units of analysis, is an experimental therapeutic target that can be directly modified through caregiver participation in the Chicago Parent Program (CPP), if increases in EF predict reduced disruptive behavior trajectories in low-income children over a short-term follow-up period, and identify which CPP-driven parenting skill improvements are the most influential in modifying EF. This work will contribute new knowledge as to whether a cost-efficient parenting intervention, developed for and with low-income families raising young children in poverty, can modify EF, a neural behavioral mechanism implicated in risk for childhood disruptive behavior problems.
Interested in participating?
Request Info4 year and older
All sexes
Interventional
Not applicable
Chicago, Illinois, 60612, United States
Location status: Recruiting
Impairments in executive functioning (EF), cognitive processes that support self-regulation, disproportionately impact children living in poverty and increase vulnerability for childhood disruptive behavior, which trigger a cascade of mental health problems and psychosocial difficulties across the lifespan. Poverty-related stress and maladaptive parenting styles have been linked to alterations of neural and behavioral EF markers in children; despite this, no studies have studied if parenting prevention programs can directly target childhood EF, and through improving EF, reduce disruptive behaviors in at-risk children. The National Institute of Mental Health (NIMH) funded K23 Mentored Patient-Oriented Research Career Development Award project seeks to conduct a mechanistic randomized clinical trial to determine whether neural-behavioral indices of childhood EF is an experimental therapeutic target that can be modified via caregiver participation in the Chicago Parent Program. Consistent with the NIMH Research Domain Criteria framework, childhood EF will be assessed across brain and behavior measurement units. The second aim of the clinical trial seeks to evaluate whether increases in childhood neural-behavioral EF mediate the effects of CPP in reducing disruptive behavior problems over a short-term follow-up. A third exploratory aim of the project is to preliminarily test whether increases in specific parenting practices (discipline, scaffolding), previously linked to individual differences in EF, mediate the effects of CPP in predicting change in childhood neural-behavioral EF. The sample will include 90 Medicaid eligible parent-child (ages 4-5 years old) dyads and will employ a novel recruitment approach where the target child will have moderate-to-severe EF delays at baseline but does not meet diagnostic criteria for a disruptive behavior disorder.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Chicago Parent Program is an evidence-based group parenting intervention designed to reduce disruptive behavior in young children (2-8 years old).
Time frame: an average of 4 months
Parents will complete the BRIEF-P to assess their child's executive functioning, and the Global Executive Composite score will be used in the analysis.
Time frame: an average of 4 months
Children will be administered the NIH Toolbox Early Childhood Cognitive Battery to assess their executive functioning.
Time frame: an average of 4 months
Children will complete the Zoo Go/No-Go computerized task while EEG is simultaneously recorded. Event-related potential components that index EF and theta spectral power and error-related interchannel phase frequency between frontocentral and frontolateral regions, will be used in the analyses.
Time frame: through study completion, an average of 16 months
Parents will complete the Child Behavior Checklist in order to assess children's disruptive behavior symptoms.
Time frame: through study completion, an average of 16 months
Parents will complete the Eyberg Child Behavior Inventory in order to assess children's disruptive behavior problems.
Time frame: through study completion, an average of 16 months
Parents will be administered the clinician administered the K-SADS-COMP, which is a web-based semi-structured interview to assess children's disruptive behavior symptoms and to determine if children meet criteria for a disruptive behavior disorder.
Time frame: an average of 4 months
Parents will complete the Home EF Environment questionnaire to assess parental use of scaffolding practices with their child at home.
Time frame: an average of 4 months
Parents will complete the Parenting Dimensions Inventory to assess parental use of different disciplinary practices across various child-rearing situations and parental nurturance.
Time frame: an average of 4 months
Parents will complete the Parenting Questionnaire to assess parental warmth, follow-through on discipline, and use of corporal punishment.
Time frame: an average of 4 months
Parents will engage in three interaction tasks (Grocery Store Task, Free-Play, Clean-up) with their child during the laboratory visits, which will be video recorded for later coding of parenting behaviors (warmth, sensitivity, harsh discipline, scaffolding) using subscales adapted from the Iowa Family Interaction Rating Scales (IFIRS).
Contact information is provided by the study sponsor or research team.
University of Illinois at Chicago
Other
Improving Brain-Behavior Markers of Preschool Executive Function Through a Group-Based Parenting Intervention for Low-Income Families
Acronym: EPIC
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