Skip to main content
OpenTrials
Completed

NCT Number: NCT01544764

Examining Adolescent Assessment, Feedback, Incentive, and Exchange (AFIX) in North Carolina

The North Carolina Immunization Branch will evaluate the use of the CDC program to improve adolescent vaccination practices (called Assessment, Feedback, Incentives, and eXchanges, or AFIX). This evaluation is the first of its kind in the nation and may have a profound impact on prevention.

AFIX has four major components: 1) Assessment of a provider's current immunization practices and vaccination levels, 2) Feedback of the assessment results and strategies to improve coverage levels, 3) Incentives to improve coverage levels, and 4) eXchange of information and resources necessary to facilitate improvement.

This program will evaluate the effectiveness of AFIX visits on affecting provider practices to increase adolescent (age 11-18) immunization. Visits include discussion of that practice's immunization rates and strategies for improving rates. The investigators will compare the changes, from baseline to 5 months, in immunization for practices receiving virtual visits (webinars), in-person visits, and no visits (control group). Thirty practices will be randomly assigned to each intervention type. The main outcomes of this study are practice-wide uptake rates of several adolescent vaccines (Tdap, HPV, and MCV4) as well as pre- and post-AFIX visit surveys focusing on recall tactics utilized by each practice. Data will be collected on practices with at least 200 adolescent patients (note: there is no patient-level data collected in this study).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Adolescent Health Services Blood-Borne Infections Communicable Diseases DNA Virus Infections Digestive System Diseases Hepadnaviridae Infections Hepatitis Hepatitis B Hepatitis, Viral, Human Immunization Infections Liver Diseases Virus Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cervical Cancer-Free North Carolina, Chapel Hill, North Carolina, United States

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pediatric and/or family practices participating in the North Carolina Immunization Program
  • A minimum of 200 active adolescent patients

Treatment and study plan

Assessment , Feedback, Incentives, and eXchange Program

Other

The NC Immunization Branch uses Adolescent AFIX (Assessment, Feedback, Incentives and eXchange) Program, a quality improvement strategy developed by the CDC to improve the immunization practices and vaccination coverage levels of public and private health care providers. It has four main components: 1) Assessment of a provider's current immunization practices and vaccination levels, 2) Feedback of the assessment results and strategies to improve coverage levels, 3) Incentives to improve coverage levels, and 4) eXchange of information and resources necessary to facilitate improvement.

Primary outcomes

  1. Change in Vaccination Rate: HPV vaccine initiation among 11-12 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (age 11-12) for the first dose of human papillomavirus (HPV) vaccine at baseline and 5 months follow-up.

Secondary outcomes

  1. Change in Vaccination Rate: HPV vaccine initiation among 13-18 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (age 13-18) for the first dose of human papillomavirus (HPV) vaccine at baseline and 5 months follow-up.

  2. Change in Vaccination Rate: Tdap vaccine among 11-12 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (age 11-12) for tetanus, diphtheria, and pertussis booster (Tdap) at baseline and 5 months follow-up.

  3. Change in Vaccination Rate: Tdap vaccine among 13-18 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (age 13-18) for tetanus, diphtheria, and pertussis booster (Tdap) at baseline and 5 months follow-up.

  4. Change in Vaccination Rate: Meningitis vaccine among 11-12 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (age 11-12) for meningococcal conjugate (i.e., meningitis vaccine) at baseline and 5 months follow-up.

  5. Change in Vaccination Rate: Meningitis vaccine among 13-18 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (age 13-18) for meningococcal conjugate (i.e., meningitis vaccine) at baseline and 5 months follow-up.

  6. Change in Vaccination Rate: HPV vaccine completion among 11-12 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (age 11-12) for the third and final dose of human papillomavirus (HPV) vaccine at baseline and 5 months follow-up.

  7. Change in Vaccination Rate: HPV vaccine completion among 13-18 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (age 13-18) for the third and final dose of human papillomavirus (HPV) vaccine at baseline and 5 months follow-up.

Other outcomes

  1. Change in Vaccination Rate: MMR among 11-12 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (ages 11-12) for measles, mumps, and rubella (MMR) vaccine at baseline and 5 months follow-up. This is a childhood vaccine that is not targeted for adolescents; however the intervention may impact MMR coverage.

  2. Change in Vaccination Rate: MMR among 13-18 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (ages 13-18) for measles, mumps, and rubella (MMR) vaccine at baseline and 5 months follow-up. This is a childhood vaccine that is not targeted for adolescents; however the intervention may impact MMR coverage.

  3. Change in Vaccination Rate: Hepatitis B vaccine among 11-12 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (ages 11-12) for hepatitis B vaccine at baseline and 5 months follow-up. This is a childhood vaccine that is not targeted for adolescents; however the intervention may impact hepatitis B vaccine coverage.

  4. Change in Vaccination Rate: Hepatitis B vaccine among 13-18 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (ages 13-18) for hepatitis B vaccine at baseline and 5 months follow-up. This is a childhood vaccine that is not targeted for adolescents; however the intervention may impact hepatitis B vaccine coverage.

  5. Change in Vaccination Rate: Varicella vaccine among 11-12 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (ages 11-12) for varicella vaccine at baseline and 5 months follow-up. This is a childhood vaccine that is not targeted for adolescents; however the intervention may impact varicella vaccine coverage.

  6. Change in Vaccination Rate: Varicella vaccine among 13-18 year olds

    Time frame: Baseline and 5 months follow-up

    We will gather practice-specific rates of coverage for adolescents (ages 13-18) for varicella vaccine at baseline and 5 months follow-up. This is a childhood vaccine that is not targeted for adolescents; however the intervention may impact varicella vaccine coverage.

Sponsors and collaborators

Lead sponsor

University of North Carolina, Chapel Hill

Other

Collaborators

  • North Carolina Division of Public Health

Registry information

Official study title

Examining Adolescent Assessment, Feedback, Incentive, and Exchange (AFIX)

Acronym: AFIX

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Mar 6, 2012
Registry last updated
Dec 18, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.