Altasciences Clinical LA, Inc.
Cypress, California, 90630, United States
Location status: Recruiting
NCT Number: NCT07225816
The purpose of this study is to investigate how the duration of fasting and temporary stopping of Glucagon-Like-Peptide 1 (GLP-1) medications affect the amount of food left in the stomach in people using liraglutide (injected), semaglutide (taken by mouth) or semaglutide (injected). The length of participants participation in the study will depend on the type of GLP-1 RA treatment participants are already using.
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Phase 1
Cypress, California, 90630, United States
Location status: Recruiting
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
For participants with T2D:
Exclusion criteria
For participants without T2D:
For participants with T2D:
Participants will receive liraglutide subcutaneously.
Participants will receive semaglutide orally.
Participants will receive semaglutide subcutaneously.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 40
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 11, Day 161
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 141
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 40
Measured as milliliters per kilogram (mL/kg).
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 11, Day 161
Measured as mL/kg.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 141
Measured as mL/kg.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 40
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 11, Day 161
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 141
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 44
Measured as count of participants
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 11, Day 165
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 8, Day 148
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 44
Measured as mL/kg
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 11, Day 165
Measured as mL/kg
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 8, Day 148
Measured as mL/kg
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 44
Measured as count of participants
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 11, Day 165
Measured as count of participants
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 8, Day 148
Measured as count of participants
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 48
Measured as count of participants
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 12, Day 171
Measured as count of participants
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 13, Day 178
Measured as count of participants
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 9, Day 153
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 10, Day 160
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 48
Measured as mL/kg
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 12, Day 171
Measured as mL/kg
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 13, Day 178
Measured as mL/kg
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 9, Day 153
Measured as mL/kg
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 10, Day 160
Measured as mL/kg
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 7, Day 48
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 12, Day 171
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 13, Day 178
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 9, Day 153
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 10, Day 160
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 2, Day 1
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 2, Day 1
Measured as mL/kg.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 2, Day 1
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 2, Day 5
Measured as count of participants.
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 2, Day 5
Measured as mL/kg
Time frame: 6, 8, 10, 12, 18 and 24 hours after start of fasting on Visit 2, Day 5
Measured as count of participants.
Contact information is provided by the study sponsor or research team.
Novo Nordisk A/S
Industry
Investigation of the Effect of Fasting Duration and Temporary Withholding of GLP-1 RAs on Retained Gastric Contents in Participants Treated With s.c. Liraglutide, Oral Semaglutide or s.c. Semaglutide
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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